• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Control of intra- and extra-cellular sulphydryl-disulphide balances with gold phosphine drugs: 31P nuclear magnetic resonance studies of human blood.

作者信息

Malik N A, Otiko G, Sadler P J

出版信息

J Inorg Biochem. 1980 Jul;12(4):317-22. doi: 10.1016/s0162-0134(00)80272-x.

DOI:10.1016/s0162-0134(00)80272-x
PMID:7411141
Abstract

Contrasting reactions of the antiarthritic complexes ClAuPEt3 and ClAu(PEt3)2 with blood have been studied by 31P nmr spectroscopy. The monophosphine complex has two binding sites in erythrocytes, probably at the SH groups of glutathione and haemoglobin. The bis complex solidifies blood via a reductive denaturation of albumin, with the release of OPet3.

摘要

相似文献

1
Control of intra- and extra-cellular sulphydryl-disulphide balances with gold phosphine drugs: 31P nuclear magnetic resonance studies of human blood.
J Inorg Biochem. 1980 Jul;12(4):317-22. doi: 10.1016/s0162-0134(00)80272-x.
2
31P nuclear-magnetic-resonance studies at 24 and 162 MHz of blood containing an anti-arthritic gold phosphine: relaxation via chemical-shift anisotropy.在24兆赫和162兆赫下对含有抗关节炎金膦的血液进行的31P核磁共振研究:通过化学位移各向异性实现弛豫。
Biochem Soc Trans. 1980 Oct;8(5):635-6. doi: 10.1042/bst0080635a.
3
Synthesis of thionato(triethylphosphine) gold(I) complexes:analogues of "auranofin," an antiarthritic drug.
J Inorg Biochem. 1990 Feb;38(2):95-100. doi: 10.1016/0162-0134(90)84017-j.
4
Interaction of the antitumor Au(I) complex [Au(Ph2P(CH2)2PPh2)2]Cl with human blood plasma, red cells, and lipoproteins: 31P and 1H NMR studies.抗肿瘤金(I)配合物[Au(Ph2P(CH2)2PPh2)2]Cl与人血浆、红细胞和脂蛋白的相互作用:31P和1H核磁共振研究
J Inorg Biochem. 1987 Dec;31(4):267-81. doi: 10.1016/0162-0134(87)80081-8.
5
[Effect of sulfur-containing compounds on experimental diabetes. X. The transport of SH and S-S compounds into red blood cells].[含硫化合物对实验性糖尿病的影响。X. SH和S-S化合物向红细胞内的转运]
Yakugaku Zasshi. 1973 Mar;93(3):379-87. doi: 10.1248/yakushi1947.93.3_379.
6
[Intracellular gold content of circulating blood cells using various gold compounds].[使用各种金化合物测定循环血细胞中的细胞内金含量]
Wien Klin Wochenschr Suppl. 1984;156:13-6.
7
Cellular and molecular pharmacology of auranofin and related gold complexes.金诺芬及相关金配合物的细胞与分子药理学
Biochem Pharmacol. 1986 Oct 15;35(20):3423-31. doi: 10.1016/0006-2952(86)90608-8.
8
In vivo antitumor activity and in vitro cytotoxic properties of bis[1,2-bis(diphenylphosphino)ethane]gold(I) chloride.二氯双[1,2-双(二苯基膦基)乙烷]金(I)的体内抗肿瘤活性和体外细胞毒性特性
Cancer Res. 1986 Nov;46(11):5486-93.
9
Thiol competition for Et3PAuS-albumin: a nonenzymatic mechanism for Et3PO formation.硫醇对三乙膦酰基金(Et3PAuS)-白蛋白的竞争:三乙膦酸乙酯(Et3PO)形成的非酶机制。
J Inorg Biochem. 1987 Jul;30(3):177-87. doi: 10.1016/0162-0134(87)80062-4.
10
Role of ascorbate and protein thiols in the release of nitric oxide from S-nitroso-albumin and S-nitroso-glutathione in human plasma.
Free Radic Biol Med. 1997;22(4):633-42. doi: 10.1016/s0891-5849(96)00378-4.

引用本文的文献

1
Nucleus-Targeted Organoiridium-Albumin Conjugate for Photodynamic Cancer Therapy.靶向细胞核的有机铱-白蛋白偶联物用于光动力癌症治疗。
Angew Chem Int Ed Engl. 2019 Feb 18;58(8):2350-2354. doi: 10.1002/anie.201813002. Epub 2019 Jan 21.