Department of Neuroscience, Valley Baptist Medical Center, Harlingen, TX, USA.
Department of Neurology, School of Medicine, University of Texas Rio Grande Valley, Edinburg, TX, USA.
Interv Neuroradiol. 2023 Aug;29(4):459-465. doi: 10.1177/15910199221090430. Epub 2022 Mar 24.
Intracranial atherosclerotic disease (ICAD) is a common cause of acute ischemic stroke. ICAD has a high rate of recurrent ischemic stroke despite recommended adequate medical treatment. Endovascular treatment of ICAD has been controversial due to high periprocedural complication in historic randomized clinical trials (RCTs). Recently, a multicenter prospective study of stent placement in patients with high grade intracranial stenosis that evaluated safety and efficacy of Balloon-mounted stents (BMS) in symptomatic ICAD showed low rates of periprocedural stroke (5.6%) than the SAMMPRIS (14.7%) and VISSIT (21.4%) trials. This review highlights the recent evolution of endovascular therapy for symptomatic ICAD.
颅内动脉粥样硬化性疾病(ICAD)是急性缺血性脑卒中的常见病因。尽管接受了推荐的充分药物治疗,ICAD 仍有很高的复发性缺血性脑卒中发生率。由于历史随机临床试验(RCT)中围手术期并发症发生率较高,ICAD 的血管内治疗一直存在争议。最近,一项对颅内狭窄程度较高的症状性 ICAD 患者进行支架置入的多中心前瞻性研究评估了球囊扩张支架(BMS)的安全性和疗效,结果显示围手术期卒中发生率较低(5.6%),低于 SAMMPRIS(14.7%)和 VISSIT(21.4%)试验。本文综述了症状性 ICAD 的血管内治疗的最新进展。