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血管成形术和支架置入术治疗有症状的颅内动脉粥样硬化性疾病:我的方法。

Angioplasty And stenting For symptomatic intracranial atherosclerotic disease: How I Do It.

机构信息

Department of Neuroscience, Valley Baptist Medical Center, Harlingen, TX, USA.

Department of Neurology, School of Medicine, University of Texas Rio Grande Valley, Edinburg, TX, USA.

出版信息

Interv Neuroradiol. 2023 Aug;29(4):459-465. doi: 10.1177/15910199221090430. Epub 2022 Mar 24.

Abstract

Intracranial atherosclerotic disease (ICAD) is a common cause of acute ischemic stroke. ICAD has a high rate of recurrent ischemic stroke despite recommended adequate medical treatment. Endovascular treatment of ICAD has been controversial due to high periprocedural complication in historic randomized clinical trials (RCTs). Recently, a multicenter prospective study of stent placement in patients with high grade intracranial stenosis that evaluated safety and efficacy of Balloon-mounted stents (BMS) in symptomatic ICAD showed low rates of periprocedural stroke (5.6%) than the SAMMPRIS (14.7%) and VISSIT (21.4%) trials. This review highlights the recent evolution of endovascular therapy for symptomatic ICAD.

摘要

颅内动脉粥样硬化性疾病(ICAD)是急性缺血性脑卒中的常见病因。尽管接受了推荐的充分药物治疗,ICAD 仍有很高的复发性缺血性脑卒中发生率。由于历史随机临床试验(RCT)中围手术期并发症发生率较高,ICAD 的血管内治疗一直存在争议。最近,一项对颅内狭窄程度较高的症状性 ICAD 患者进行支架置入的多中心前瞻性研究评估了球囊扩张支架(BMS)的安全性和疗效,结果显示围手术期卒中发生率较低(5.6%),低于 SAMMPRIS(14.7%)和 VISSIT(21.4%)试验。本文综述了症状性 ICAD 的血管内治疗的最新进展。

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