Faculty of Medicine and Dentistry, University of Plymouth, Plymouth, UK.
Br J Anaesth. 2022 Jul;129(1):7-10. doi: 10.1016/j.bja.2022.02.031. Epub 2022 Mar 21.
Intensive care unit (ICU) sedation with sevoflurane is associated with nephrogenic diabetes insipidus. Given that isoflurane is now licenced (in Europe) for ICU sedation and has Investigational New Drug status in the USA, evidence indicates that clinicians should stop using sevoflurane in this indication except in the context of clinical trials.
七氟醚在重症监护病房（ICU）镇静中与肾源性尿崩症有关。鉴于异氟醚现已获准（在欧洲）用于 ICU 镇静，并且在美国具有新药研究（IND）地位，有证据表明，临床医生应停止在该适应证中使用七氟醚，除非在临床试验背景下。
