家族性腺瘤性息肉病患儿的甲状腺结节。
Thyroid Nodules in Children With Familial Adenomatous Polyposis.
机构信息
Thyroid Center, Boston Children's Hospital, Boston, Massachusetts, USA.
Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
出版信息
Am J Gastroenterol. 2022 Jul 1;117(7):1166-1168. doi: 10.14309/ajg.0000000000001747. Epub 2022 Mar 25.
INTRODUCTION
Ultrasound screening for thyroid cancer is recommended in familial adenomatous polyposis (FAP). This study investigated the prevalence of thyroid neoplasia in children with FAP.
METHODS
Cross-sectional study of children with FAP at an academic hospital. Clinical and ultrasound data were analyzed for the prevalence of thyroid nodules and cancer.
RESULTS
Of 37 children with FAP, 8 (22%) had thyroid nodules and 2 (5%) had thyroid cancer. Nodules (30%) and cancer (9%) were more common among female subjects and rare among male subjects.
DISCUSSION
Thyroid ultrasound screening in adolescence may benefit female subjects with FAP but has limited utility in male subjects.
简介
在家族性腺瘤性息肉病（FAP）中推荐进行甲状腺癌的超声筛查。本研究调查了 FAP 患儿中甲状腺肿瘤的患病率。
方法
对学术医院的 FAP 患儿进行横断面研究。分析了临床和超声数据，以了解甲状腺结节和癌症的患病率。
结果
在 37 名 FAP 患儿中，有 8 名（22%）有甲状腺结节，有 2 名（5%）患有甲状腺癌。女性中结节（30%）和癌症（9%）更为常见，而男性中则罕见。
讨论
青春期甲状腺超声筛查可能有益于 FAP 的女性患者，但对男性患者的作用有限。
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