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胃肠道移植物抗宿主病

Graft-versus-host disease of the gastrointestinal tract.

作者信息

Schuttevaer H M, Kroon H M, Chandie Shaw P

出版信息

Diagn Imaging Clin Med. 1986;55(4-5):254-61.

PMID:3533389
Abstract

Forty-two gastrointestinal examinations performed in 24 patients with a history of bone marrow transplantation were analyzed retrospectively. All patients were clinically suspected of a graft-versus-host disease (GVHD) involving the alimentary tract. No specific abnormalities were found in the esophagus or the stomach. Radiographic features of a GVHD of the small bowel are: edema of mucosal folds in ileum and jejunum; effacement of folds towards the ileum; thickening of the bowel wall, and spasms and stenosis with prestenotic dilatation. In the active phase the bowel appears to be shortened. A short transit time was not a specific finding. Follow-up examinations showed partial regression of these findings. Radiological findings in the colon consisted of loss of haustration, thumbprinting, spasms and ulcerations.

摘要

回顾性分析了24例有骨髓移植病史患者进行的42次胃肠道检查。所有患者临床上均怀疑有涉及消化道的移植物抗宿主病(GVHD)。食管或胃未发现特异性异常。小肠GVHD的影像学特征为:回肠和空肠黏膜皱襞水肿;皱襞向回肠方向消失;肠壁增厚,以及伴有狭窄前扩张的痉挛和狭窄。在活动期,肠管似乎缩短。转运时间短并非特异性表现。随访检查显示这些表现部分消退。结肠的影像学表现包括结肠袋消失、拇指印征、痉挛和溃疡。

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