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严重肥胖会导致择期结肠切除术治疗慢性憩室病后的预后更差。

Severe Obesity Contributes to Worse Outcomes After Elective Colectomy for Chronic Diverticular Disease.

作者信息

Yoon Paul, Rajasekar Ganesh, Nuño Miriam, Raskin Elizabeth, Lyo Victoria

机构信息

Department of Surgery, University of California Davis Medical Center, 2335 Stockton Blvd., NAOB 6113, Sacramento, CA, 95817, USA.

出版信息

J Gastrointest Surg. 2022 Jul;26(7):1472-1481. doi: 10.1007/s11605-022-05303-2. Epub 2022 Mar 25.

Abstract

BACKGROUND

Both obesity and chronic diverticular disease (DD) are on the rise. Understanding surgical outcomes for patients with obesity undergoing colectomy for DD is imperative to improve care and minimize complications. Our objective was to investigate the impact of obesity on outcomes after elective colectomy specifically for chronic DD.

METHODS

Using the American College of Surgeons National Surgical Quality Improvement Program database from 2012 to 2018, patients who underwent elective colectomy for chronic DD were grouped into four body mass index categories. Baseline characteristics, surgical approach and procedure, and 30-day morbidity and mortality were assessed.

RESULTS

Of 24,559 patients, 21.7% were of normal weight, 35.8% were overweight, 35.9% were obese, and 6.6% were severely obese. Patients with severe obesity were younger, more functionally dependent, and had more comorbidities (all P [Formula: see text] 0.0001). Patients with severe obesity were more likely to have unplanned conversion to open surgery from laparoscopic and robotic approaches (AOR 2.15, 95% CI 1.24-3.70). Obesity class did not significantly affect the type of surgical procedure patients underwent (Hartmann's, colectomy with anastomosis and diversion, or colectomy with primary anastomosis). There were increased odds of any perioperative complications (AOR 1.43, 95% CI 1.19-1.71) and non-home discharge (AOR 2.39, 95% CI 1.59-3.57) in patients with severe obesity compared to normal weight patients.

CONCLUSIONS

Obesity is associated with poorer outcomes in patients undergoing elective colectomy for chronic DD. Futures studies to examine the impact of preemptive weight loss to improve outcomes after elective colectomy for chronic sequelae of DD are needed.

摘要

背景

肥胖症和慢性憩室病(DD)的发病率均呈上升趋势。了解肥胖患者因DD接受结肠切除术的手术结果对于改善护理和减少并发症至关重要。我们的目的是研究肥胖对择期结肠切除术治疗慢性DD术后结果的影响。

方法

利用2012年至2018年美国外科医师学会国家外科质量改进计划数据库,将因慢性DD接受择期结肠切除术的患者分为四个体重指数类别。评估基线特征、手术方式和操作以及30天发病率和死亡率。

结果

在24559例患者中,体重正常者占21.7%,超重者占35.8%,肥胖者占35.9%,重度肥胖者占6.6%。重度肥胖患者更年轻,功能依赖性更强,合并症更多(所有P[公式:见正文]<0.0001)。重度肥胖患者更有可能从腹腔镜和机器人手术方式转为非计划的开放手术(调整后比值比2.15,95%置信区间1.24-3.70)。肥胖等级对患者接受的手术类型(哈特曼手术、吻合和转流结肠切除术或一期吻合结肠切除术)没有显著影响。与体重正常的患者相比,重度肥胖患者发生任何围手术期并发症(调整后比值比1.43,95%置信区间1.19-1.71)和非回家出院(调整后比值比2.39,95%置信区间1.59-3.57)的几率增加。

结论

肥胖与因慢性DD接受择期结肠切除术的患者预后较差有关。需要进一步研究以探讨预防性体重减轻对改善因DD慢性后遗症接受择期结肠切除术后结果的影响。

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