Suppr超能文献

根据 BMI 和肥胖代谢类别选择的器官和内分泌并发症:单一生殖内分泌中心研究。

Selected Organ and Endocrine Complications According to BMI and the Metabolic Category of Obesity: A Single Endocrine Center Study.

机构信息

Department of Endocrinology, Metabolism and Internal Diseases, Poznan University of Medical Sciences, 61-701 Poznan, Poland.

Department of Gastroenterology, Dietetics and Internal Diseases, Poznan University of Medical Sciences, 61-701 Poznan, Poland.

出版信息

Nutrients. 2022 Mar 20;14(6):1307. doi: 10.3390/nu14061307.

Abstract

Obesity is a chronic and complex disease associated with metabolic, organ and endocrine complications. In the study, we analyzed a group of 105 patients suffering from obesity without any other previously recognized serious disorders who had been referred to a single endocrine center. The study aimed to assess the prevalence of selected organ and endocrine complications by subdividing the group, firstly according to body mass index (BMI) and secondly with regard to metabolic syndrome (MetS), pre-MetS and the metabolically healthy obesity (MHO) category. We have observed that in our groups, the prevalence of hyperlipidemia, hypertension, asthma, obstructive sleep apnea (OSA) depended on BMI category, whereas the incidence of hyperlipidemia, hypertension, OSA, hypothyroidism, non-alcoholic fatty liver disease, prediabetes, and type 2 diabetes was related to the metabolic category. We concluded that the distribution of particular organ and endocrine complications change significantly with increased BMI and with the shift from MHO to pre-MetS and MetS. Thus, to determine the risk of organ and endocrine complications more effectively, BMI and metabolic status should be assessed during the examination of patients with obesity.

摘要

肥胖是一种与代谢、器官和内分泌并发症相关的慢性和复杂疾病。在这项研究中,我们分析了一组 105 名患有肥胖症但没有任何其他先前被识别的严重疾病的患者,这些患者被转介到一个内分泌中心。该研究旨在通过将患者群体首先根据体重指数 (BMI) 进行细分,其次根据代谢综合征 (MetS)、前 MetS 和代谢健康型肥胖 (MHO) 类别,评估选定的器官和内分泌并发症的患病率。我们观察到,在我们的分组中,血脂异常、高血压、哮喘、阻塞性睡眠呼吸暂停 (OSA) 的患病率取决于 BMI 类别,而血脂异常、高血压、OSA、甲状腺功能减退症、非酒精性脂肪性肝病、糖尿病前期和 2 型糖尿病的发病率与代谢类别有关。我们得出结论,随着 BMI 的增加以及从 MHO 到前 MetS 和 MetS 的转变,特定器官和内分泌并发症的分布发生了显著变化。因此,为了更有效地确定器官和内分泌并发症的风险,在检查肥胖症患者时应评估 BMI 和代谢状况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0a0/8954480/dabefb790aab/nutrients-14-01307-g001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验