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使用 GOAL 问卷作为阻塞性睡眠呼吸暂停的标准化筛查工具。

Utilization of the GOAL questionnaire as a standardized screening tool for obstructive sleep apnea.

机构信息

Department of Respiratory and Critical Care Medicine, The Second Hospital of Shanxi Medical University, No. 382, Wuyi Road, Xinghualing District, Taiyuan, Shanxi, China.

Department of Respiratory and Critical Care Medicine, The First Hospital of Shanxi Medical University, No. 85, Jiefang South Road, Yingze District, Taiyuan, Shanxi, China.

出版信息

Sci Rep. 2023 Apr 4;13(1):5489. doi: 10.1038/s41598-023-31247-x.

DOI:10.1038/s41598-023-31247-x
PMID:37015938
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10073216/
Abstract

The purpose of our study was to evaluate the application value of the GOAL questionnaire in screening obstructive sleep apnea (OSA) and to compare it with the other three questionnaires in sleep clinics. A cross-sectional study was conducted in 436 patients who had undergone nocturnal polysomnography in the sleep unit of the First Hospital of Shanxi Medical University between September 2021 and May 2022, and all patients completed the four questionnaires (GOAL questionnaire, STOP-Bang questionnaire, NoSAS score and No-Apnea score) truthfully, and the patients were divided into 3 groups: AHI ≥ 5 events/h group, AHI ≥ 15 events/h group and AHI ≥ 30 events/h group. The predictive effect of the questionnaire on different AHI cut-off values was calculated, and performance of four questionnaires was assessed by the discriminatory ability. This study ultimately included 410 patients, and there were statistically significant differences in gender, age, BMI, neck circumference, clinical symptoms, hypertension, diabetes, AHI, and minimum oxygen saturation between OSA and non-OSA groups (P < 0.05). The AUC for No-Apnea score was 0.79, the AUC for STOP-Bang questionnaire was 0.86, the AUC for NoSAS score was 0.81, and the AUC for GOAL questionnaire was 0.77. These four questionnaires were effective in screening OSA when AHI ≥ 15 events/h. Similar to No-Apnea score, STOP-Bang score and NoSAS score, GOAL questionnaire has a good predictive value for OSA, which is a questionnaire suitable for primary health-care centers and clinics.

摘要

我们的研究目的是评估 GOAL 问卷在筛查阻塞性睡眠呼吸暂停(OSA)中的应用价值,并与睡眠诊所中的其他三种问卷进行比较。这是一项在山西医科大学第一医院睡眠科进行的 436 例患者的横断面研究,这些患者在 2021 年 9 月至 2022 年 5 月期间进行了夜间多导睡眠图检查,所有患者均如实完成了四种问卷(GOAL 问卷、STOP-Bang 问卷、NoSAS 评分和 No-Apnea 评分),并将患者分为 3 组:AHI≥5 次/小时组、AHI≥15 次/小时组和 AHI≥30 次/小时组。计算了问卷对不同 AHI 截断值的预测效果,并通过判别能力评估了四种问卷的性能。本研究最终纳入 410 例患者,OSA 组和非 OSA 组在性别、年龄、BMI、颈围、临床症状、高血压、糖尿病、AHI 和最低血氧饱和度方面存在统计学差异(P<0.05)。No-Apnea 评分的 AUC 为 0.79,STOP-Bang 问卷的 AUC 为 0.86,NoSAS 评分的 AUC 为 0.81,GOAL 问卷的 AUC 为 0.77。当 AHI≥15 次/小时时,这四种问卷在筛查 OSA 方面均有效。与 No-Apnea 评分、STOP-Bang 评分和 NoSAS 评分类似,GOAL 问卷对 OSA 具有良好的预测价值,是一种适合基层医疗保健中心和诊所的问卷。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c55c/10073216/a55b27d8b6d5/41598_2023_31247_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c55c/10073216/ba6847f449f0/41598_2023_31247_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c55c/10073216/e602c74eaf21/41598_2023_31247_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c55c/10073216/9788fdc67bd0/41598_2023_31247_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c55c/10073216/a55b27d8b6d5/41598_2023_31247_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c55c/10073216/ba6847f449f0/41598_2023_31247_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c55c/10073216/e602c74eaf21/41598_2023_31247_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c55c/10073216/9788fdc67bd0/41598_2023_31247_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c55c/10073216/a55b27d8b6d5/41598_2023_31247_Fig4_HTML.jpg

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