Grigor'ev G I, Petrova T R
Farmakol Toksikol. 1986 Sep-Oct;49(5):94-7.
Effects of ethmozine and ritmilen were studied in 75 patients with different disorders of cardiac rhythm predominantly proceeding in the form of extrasystole arrhythmia. The drugs were found to exert a distinct antiaggregant action on platelets and erythrocytes which was particularly pronounced at intravenous administration and transiently increased the number of leukocytes and their aggregation. A decrease of platelet aggregation was accompanied by an increase of their number and rejuvenascence of thrombocytogram. A marked antiarrhythmic effect was seen in 66% of patients, in the remaining patients cardiac extracontractions became more rare.
对75例主要表现为早搏性心律失常的不同心律紊乱患者研究了乙吗噻嗪和利脉啉的作用。发现这些药物对血小板和红细胞有明显的抗聚集作用，静脉给药时尤为显著，并可使白细胞数量及其聚集作用短暂增加。血小板聚集减少的同时，其数量增加，血小板图恢复正常。66%的患者有明显的抗心律失常作用，其余患者心脏期外收缩变得更为少见。
