Chen P C, Wu C S, Liaw Y F
Gastrointest Endosc. 1986 Oct;32(5):319-23. doi: 10.1016/s0016-5107(86)71875-0.
An uncontrolled study for the assessment of the hemostatic effects of endoscopically injected hypertonic saline-epinephrine (HS-E) solution and pure ethanol (PE) was carried out in 67 patients with nonvariceal gastrointestinal bleeding. The HS-E group included duodenal ulcer (18), gastric ulcer (9), gastric cancer (2), polyp (2), marginal ulcer (1), and esophageal cancer (1). Bleeding was active in 15 (pulsating, 3; oozing, 12). The hemostatic effect was permanent in 29 cases (87.9%) but failed in four cases (12.1%). The PE group consisted of 34 patients with duodenal ulcer (25), gastric ulcer (4), polyp (2), marginal ulcer (2), and gastric cancer (1). There was active bleeding in 14 (pulsating, 3; oozing, 11). The hemostatic effect was permanent in 31 cases (91.2%), temporary in 1 case (2.9%), and failed in 2 cases (5.9%). We conclude that endoscopic local injection with HS-E or PE is a simple maneuver with reasonable cost, high safety, and satisfactory hemostatic efficacy in the treatment of nonvariceal gastrointestinal bleeding.
对67例非静脉曲张性上消化道出血患者进行了一项评估内镜下注射高渗盐水肾上腺素（HS-E）溶液和纯乙醇（PE）止血效果的非对照研究。HS-E组包括十二指肠溃疡患者18例、胃溃疡患者9例、胃癌患者2例、息肉患者2例、边缘溃疡患者1例和食管癌患者1例。其中15例有活动性出血（搏动性出血3例，渗血12例）。止血效果永久性有效29例（87.9%），无效4例（12.1%）。PE组由34例患者组成，其中十二指肠溃疡患者25例、胃溃疡患者4例、息肉患者2例、边缘溃疡患者2例和胃癌患者1例。有14例存在活动性出血（搏动性出血3例，渗血11例）。止血效果永久性有效31例（91.2%），暂时性有效1例（2.9%），无效2例（5.9%）。我们得出结论，内镜下局部注射HS-E或PE治疗非静脉曲张性上消化道出血是一种操作简单、成本合理、安全性高且止血效果满意的方法。
