Panontin Juliane Farinelli, Barbosa Robson Dos Santos, Isaac Vera, Seibert Carla Simone, Scapin Elisandra
Postgraduate Program in Environmental Sciences - Ciamb, Federal University of Tocantins, Palmas, TO, Brazil.
Postgraduate Program in Biodiversity and Biotechnology - BIONORTE, Federal University of Tocantins, Palmas, TO, Brazil.
Nat Prod Res. 2022 Dec;36(23):6121-6125. doi: 10.1080/14786419.2022.2053968. Epub 2022 Mar 25.
The goal of this work was to chemically characterise extracts to develop an antioxidant serum formulation. Stem and bark extracts were prepared using 70% hydroethanol solution by Sohxlet and ultrasound assisted extraction. The content of total phenols, flavonoids, and antioxidant activity were evaluated, and chemical characterization was performed by HPLC -detector UV-VIS (SPD - 10 A). The formulation was developed with stem extract (0.250 mg/g) in hydroxyethylcellulose fluid gel. Stem extracts had higher total phenols and flavonoids, and higher antioxidant activity than bark extracts. The formulation presented low viscosity, a yellowish colour, 81.28% ± 0.14 of antioxidant activity. In the stability test, the physicochemical characteristics showed small variations, remaining more stable at a temperature of 5 °C, with an antioxidant activity of 64.81% ± 0.75. Therefore, the stem of has the potential to be used in antioxidant formulations.
