King Fahad Medical City, Riyadh, Saudi Arabia.
College of Medicine, King Saud University, Riyadh, Saudi Arabia.
BMC Neurol. 2022 Mar 25;22(1):120. doi: 10.1186/s12883-022-02632-2.
Multiple sclerosis (MS) is an inflammatory chronic disease that is characterized by an increased prevalence of adverse mental health outcomes in patients with MS (pwMS). The main aim of this study is to investigate the factors of depression and anxiety in pwMS in the Kingdom of Saudi Arabia (KSA).
This is a cross-sectional study conducted in KSA during the period from March to June 2020. Participants were recruited from the Neuroimmunology clinics in King Fahad Medical City (KFMC) and King Saud University medical city (KSUMC)in Riyadh City, KSA. The Hospital Anxiety and Depression Scale (HADS) was used to measure depression and anxiety. Fatigue Severity Scale (FSS) was used to measure fatigue in pwMS. A simple random sampling technique was utilized to select participants and the data were analyzed using SPSS v.24.0.
A total of 529 participants participated in this study with a response rate of 53.1%. The prevalences of anxiety and depression were 35.3% and 19.7%, respectively. The findings also revealed that depression was more likely to be significantly affected by being male, low education, unemployment, physical inactivity, and fatigue but the anxiety was significantly affected by region, unemployment, short duration since last MS relapse, physical inactivity, and fatigue.
Anxiety and depression are not uncommon in pwMS. Given their impact on the lives of affected patients, early detection and management of these symptoms and their associated factors are crucial.
多发性硬化症（MS）是一种炎症性慢性疾病，其特点是 MS 患者（pwMS）的心理健康不良结局发生率增加。本研究的主要目的是调查沙特阿拉伯王国（KSA）pwMS 中抑郁和焦虑的相关因素。
这是一项在 2020 年 3 月至 6 月期间在 KSA 进行的横断面研究。参与者从 KFMC 和 KSUMC 的神经免疫科招募。采用医院焦虑抑郁量表（HADS）评估抑郁和焦虑，采用疲劳严重程度量表（FSS）评估 pwMS 的疲劳。采用简单随机抽样技术选择参与者，使用 SPSS v.24.0 对数据进行分析。
共有 529 名参与者参与了本研究，应答率为 53.1%。焦虑和抑郁的患病率分别为 35.3%和 19.7%。研究结果还表明，抑郁更可能受到男性、低教育程度、失业、缺乏身体活动和疲劳的显著影响，而焦虑则显著受到地区、失业、上次 MS 复发后时间较短、缺乏身体活动和疲劳的影响。
焦虑和抑郁在 pwMS 中并不少见。鉴于这些症状对受影响患者生活的影响，早期发现和管理这些症状及其相关因素至关重要。
