State Key Laboratory of Food Science and Technology, China-Canada Joint Laboratory of Food Science and Technology (Nanchang), Key Laboratory of Bioactive Polysaccharides of Jiangxi Province, Nanchang University, 235 Nanjing East Road, Nanchang 330047, PR China.
State Key Laboratory of Food Science and Technology, China-Canada Joint Laboratory of Food Science and Technology (Nanchang), Key Laboratory of Bioactive Polysaccharides of Jiangxi Province, Nanchang University, 235 Nanjing East Road, Nanchang 330047, PR China.
Carbohydr Polym. 2022 Jun 15;286:119271. doi: 10.1016/j.carbpol.2022.119271. Epub 2022 Feb 23.
Xylan as the second most abundant indigestible carbohydrate found in nature attracts great interests of researchers, nutritionist and consumers due to its various health benefits. However, accumulated studies indicate the interactions with gut microbiota greatly affect these benefits, and significant progress has been made over the past few years to understand how microbes utilize xylan at gene level. In this review, we focused on gut xylanolytic microbes and xylan's physico-chemical features, summarized the xylanases needed for complete xylan decomposition, their substrate specificity and the presence in gut microbes, as well as microbial degradation of xylan in single strain mode and cooperation mode. Xylan utilization system were discussed with different phyla. Furthermore, the implications on intestinal homeostasis and metabolic response were reviewed with clinical effects emphasized, and highlight is placed on specific gut microbes and the complexity of xylan structure to provide a clue for the inconsistent results in human studies. CHEMICAL COMPOUNDS: xylan; arabinoxylan, glucuronoxylans; glucuronoarabinoxylans; xylo-oligosaccharides; arabinoxylo-oligosaccharides.
木聚糖作为自然界中第二丰富的不可消化碳水化合物，由于其多种健康益处，引起了研究人员、营养学家和消费者的极大兴趣。然而，积累的研究表明，与肠道微生物群的相互作用极大地影响了这些益处，在过去几年中，人们在理解微生物如何在基因水平上利用木聚糖方面取得了重大进展。在这篇综述中，我们重点介绍了肠道木聚糖分解菌和木聚糖的理化特性，总结了完全分解木聚糖所需的木聚糖酶、它们的底物特异性以及在肠道微生物中的存在，以及微生物在单菌株模式和合作模式下对木聚糖的降解。讨论了不同门的木聚糖利用系统。此外，还综述了对肠道内稳态和代谢反应的影响，并强调了临床效果，重点介绍了特定的肠道微生物和木聚糖结构的复杂性，为人类研究中不一致的结果提供了线索。化学化合物：木聚糖；阿拉伯木聚糖、葡糖醛酸木聚糖；葡糖醛酸阿拉伯木聚糖；木二糖；阿拉伯木二糖。
