Division of Neurosurgery, Department of Surgery, Thammasat University Hospital, Faculty of Medicine, Thammasat University, Pathumthani, Thailand.
Department of Otolaryngology-Head and Neck Surgery, University of Missouri, Columbia, Missouri, USA.
World Neurosurg. 2022 Jun;162:66. doi: 10.1016/j.wneu.2022.03.072. Epub 2022 Mar 23.
The transorbital endoscopic approach has been increasingly employed in the management of skull base disease. We present a case of a 48-year-old woman with a 2-month history of progressively worsening headache referred to our neurosurgery division after a new-onset generalized seizure. On examination, she was found to have diminished olfaction with no additional findings, including no visual or cognitive deficits. Preoperative imaging revealed a large anterior fossa mass originating at the left olfactory groove with leftward extension and prominent anterior and posterior ethmoidal arterial feeders. A left-sided transorbital approach was planned to address the tumor. The lesion was resected without incident using a pure transorbital endoscopic technique. The microscope was brought into the field at the end of the procedure to aid with hemostasis of the surgical bed. The patient recovered without surgical complications. Histopathology revealed a World Health Organization grade I olfactory groove meningioma. Postoperative imaging confirmed gross total tumor resection without evidence of recurrence. This case highlights the application of the transorbital endoscopic approach in the management of anterior cranial base tumors. Advantages of this approach include minimal invasive access, avoidance of brain retraction, and ease for early tumor devascularization.
经眶内窥镜入路在颅底疾病的治疗中得到了越来越多的应用。我们报告了一例 48 岁女性病例,该患者在出现新发全面性癫痫发作后,因进行性加重的头痛病史 2 个月,被转至神经外科。检查发现嗅觉减退,无其他发现,包括视力或认知缺陷。术前影像学显示起源于左侧嗅沟的大型前颅窝肿块,向左侧延伸,并有明显的前筛动脉和后筛动脉供血。计划采用左侧经眶内窥镜入路来处理肿瘤。使用纯经眶内窥镜技术无事故地切除了病变。在手术结束时将显微镜带入视野,以帮助止血手术床。患者术后无手术并发症恢复。组织病理学显示为世界卫生组织一级嗅沟脑膜瘤。术后影像学证实肿瘤大体全切除,无复发证据。该病例强调了经眶内窥镜入路在治疗前颅底肿瘤中的应用。该方法的优点包括微创入路、避免脑牵拉和便于早期肿瘤血管化。