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1
Melatonin use for SARS-CoV-2 infection: Time to diversify the treatment portfolio.褪黑素用于新型冠状病毒感染:是时候使治疗方案多样化了。
J Med Virol. 2022 Jul;94(7):2928-2930. doi: 10.1002/jmv.27740. Epub 2022 Apr 12.
2
Melatonin: highlighting its use as a potential treatment for SARS-CoV-2 infection.褪黑素:强调其在治疗 SARS-CoV-2 感染方面的潜在用途。
Cell Mol Life Sci. 2022 Feb 20;79(3):143. doi: 10.1007/s00018-021-04102-3.
3
Potential Therapeutic Approach of Melatonin against Omicron and Some Other Variants of SARS-CoV-2.褪黑素对抗奥密克戎和其他一些 SARS-CoV-2 变体的潜在治疗方法。
Molecules. 2022 Oct 16;27(20):6934. doi: 10.3390/molecules27206934.
4
Pharmacological agents under investigation in the treatment of coronavirus disease 2019 and the importance of melatonin.正在研究用于治疗 2019 年冠状病毒病的药物及褪黑素的重要性。
Fundam Clin Pharmacol. 2021 Feb;35(1):62-75. doi: 10.1111/fcp.12589. Epub 2020 Oct 14.
5
Melatonin is a potential adjuvant to improve clinical outcomes in individuals with obesity and diabetes with coexistence of Covid-19.褪黑素可能是一种辅助剂,可改善患有肥胖症和糖尿病且同时感染新冠病毒的个体的临床结局。
Eur J Pharmacol. 2020 Sep 5;882:173329. doi: 10.1016/j.ejphar.2020.173329. Epub 2020 Jun 30.
6
In-silico drug repurposing study predicts the combination of pirfenidone and melatonin as a promising candidate therapy to reduce SARS-CoV-2 infection progression and respiratory distress caused by cytokine storm.计算机药物重定位研究预测,联合使用吡非尼酮和褪黑素可能成为一种有前途的治疗方法,以减轻细胞因子风暴引起的 SARS-CoV-2 感染进展和呼吸窘迫。
PLoS One. 2020 Oct 2;15(10):e0240149. doi: 10.1371/journal.pone.0240149. eCollection 2020.
7
Therapeutic Benefits of Melatonin against COVID-19.褪黑素防治 COVID-19 的治疗益处。
Neuroimmunomodulation. 2023;30(1):196-205. doi: 10.1159/000531550. Epub 2023 Jun 19.
8
COVID-19: Rational discovery of the therapeutic potential of Melatonin as a SARS-CoV-2 main Protease Inhibitor.COVID-19:褪黑素作为 SARS-CoV-2 主要蛋白酶抑制剂的治疗潜力的合理发现。
Int J Med Sci. 2020 Jul 30;17(14):2133-2146. doi: 10.7150/ijms.48053. eCollection 2020.
9
Possible Application of Melatonin in Long COVID.褪黑素在长新冠中的可能应用。
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10
Role of melatonin in the treatment of COVID-19; as an adjuvant through cluster differentiation 147 (CD147).褪黑素在治疗 COVID-19 中的作用;作为簇分化抗原 147(CD147)的佐剂。
Mol Biol Rep. 2020 Oct;47(10):8229-8233. doi: 10.1007/s11033-020-05830-8. Epub 2020 Sep 12.

引用本文的文献

1
A mid‑pandemic night's dream: Melatonin, from harbinger of anti‑inflammation to mitochondrial savior in acute and long COVID‑19 (Review).大流行期间的一个午夜之梦:褪黑素,从抗炎先兆到急性和长新冠 COVID-19 中的线粒体救星(综述)。
Int J Mol Med. 2024 Mar;53(3). doi: 10.3892/ijmm.2024.5352. Epub 2024 Feb 1.
2
Melatonin: Facts, Extrapolations and Clinical Trials.褪黑素:事实、推断和临床试验。
Biomolecules. 2023 Jun 5;13(6):943. doi: 10.3390/biom13060943.
3
Access to the COVID-19 Vaccine.获取 COVID-19 疫苗。
Int J Environ Res Public Health. 2022 Sep 3;19(17):11054. doi: 10.3390/ijerph191711054.
4
Melatonin effect on platelets and coagulation: Implications for a prophylactic indication in COVID-19.褪黑素对血小板和凝血的影响:在 COVID-19 中预防应用的意义。
Life Sci. 2022 Oct 15;307:120866. doi: 10.1016/j.lfs.2022.120866. Epub 2022 Aug 6.

本文引用的文献

1
Melatonin: highlighting its use as a potential treatment for SARS-CoV-2 infection.褪黑素:强调其在治疗 SARS-CoV-2 感染方面的潜在用途。
Cell Mol Life Sci. 2022 Feb 20;79(3):143. doi: 10.1007/s00018-021-04102-3.
2
Efficacy of melatonin in the treatment of patients with COVID-19: A systematic review and meta-analysis of randomized controlled trials.褪黑素治疗 COVID-19 患者的疗效:随机对照试验的系统评价和荟萃分析。
J Med Virol. 2022 May;94(5):2102-2107. doi: 10.1002/jmv.27595. Epub 2022 Jan 23.
3
The Effect of Melatonin on Thrombosis, Sepsis and Mortality Rate in COVID-19 Patients.褪黑素对 COVID-19 患者血栓、脓毒症和死亡率的影响。
Int J Infect Dis. 2022 Jan;114:79-84. doi: 10.1016/j.ijid.2021.10.012. Epub 2021 Oct 12.
4
Melatonin effects on sleep quality and outcomes of COVID-19 patients: An open-label, randomized, controlled trial.褪黑素对 COVID-19 患者睡眠质量和结局的影响:一项开放标签、随机、对照试验。
J Med Virol. 2022 Jan;94(1):263-271. doi: 10.1002/jmv.27312. Epub 2021 Sep 8.
5
A Pilot Study on Controlling Coronavirus Disease 2019 (COVID-19) Inflammation Using Melatonin Supplement.褪黑素补充剂控制 2019 冠状病毒病(COVID-19)炎症的初步研究。
Iran J Allergy Asthma Immunol. 2021 Aug 7;20(4):494-499.
6
What if melatonin could help patients with severe COVID-19?如果褪黑素能帮助患有严重新冠肺炎的患者会怎样?
J Clin Sleep Med. 2022 Jan 1;18(1):335-336. doi: 10.5664/jcsm.9554.
7
Efficacy of a Low Dose of Melatonin as an Adjunctive Therapy in Hospitalized Patients with COVID-19: A Randomized, Double-blind Clinical Trial.褪黑素低剂量作为 COVID-19 住院患者辅助治疗的疗效:一项随机、双盲临床试验。
Arch Med Res. 2022 Jan;53(1):79-85. doi: 10.1016/j.arcmed.2021.06.006. Epub 2021 Jun 23.
8
Targeting Host Defense System and Rescuing Compromised Mitochondria to Increase Tolerance against Pathogens by Melatonin May Impact Outcome of Deadly Virus Infection Pertinent to COVID-19.通过褪黑素靶向宿主防御系统和挽救受损的线粒体来提高对病原体的耐受性可能会影响与 COVID-19 相关的致命病毒感染的结果。
Molecules. 2020 Sep 25;25(19):4410. doi: 10.3390/molecules25194410.
9
COVID-19: Rational discovery of the therapeutic potential of Melatonin as a SARS-CoV-2 main Protease Inhibitor.COVID-19:褪黑素作为 SARS-CoV-2 主要蛋白酶抑制剂的治疗潜力的合理发现。
Int J Med Sci. 2020 Jul 30;17(14):2133-2146. doi: 10.7150/ijms.48053. eCollection 2020.
10
Beneficial actions of melatonin in the management of viral infections: a new use for this "molecular handyman"?褪黑素在病毒感染管理中的有益作用:这种“分子杂工”的新用途?
Rev Med Virol. 2012 Sep;22(5):323-38. doi: 10.1002/rmv.1714. Epub 2012 Apr 18.

Melatonin use for SARS-CoV-2 infection: Time to diversify the treatment portfolio.

作者信息

Reiter Russel J, Sharma Ramaswamy, Tan Dun-Xian, Neel Richard L, Simko Fedor, Manucha Walter, Rosales-Corral Sergio, Cardinali Daniel P

机构信息

Department of Cell Systems and Anatomy, Long School of Medicine, UT Health San Antonio, San Antonio, Texas, USA.

Alcasian Care Enterprises, Castroville, Texas, USA.

出版信息

J Med Virol. 2022 Jul;94(7):2928-2930. doi: 10.1002/jmv.27740. Epub 2022 Apr 12.

DOI:10.1002/jmv.27740
PMID:35338491
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9088493/
Abstract
摘要