Faculty of Dentistry, The University of Hong Kong, Hong Kong S.A.R; T.H. Chan School of Public Health, Harvard University, Boston, MA, USA.
Faculty of Dentistry, The University of Hong Kong, Hong Kong S.A.R.
Photodiagnosis Photodyn Ther. 2022 Jun;38:102828. doi: 10.1016/j.pdpdt.2022.102828. Epub 2022 Mar 23.
To compare the validity of DIAGNOdent pen™ 2190 and clinical photographs in the diagnosis (presence or absence) and assessment of white spot lesions (WSLs) during multi-bracketed fixed orthodontic treatment.
A total of 1607 readings from 99 patients were obtained using DIAGNOdent pen™ 2190, clinical photographs, and visual assessment criteria to assess WSLs at 6 -, 12- and 18 months after bonding of brackets. Receiver operating characteristic curves were constructed, and areas under the curve (AUC) were calculated to assess the presence or absence of WSLs and distinguish the severity of WSLs as slight or severe. Sensitivities, specificities, and AUC were calculated for outcomes at an alpha of 0.05 and 95% confidence intervals (CIs).
The values of sensitivity and specificity of DIAGNOdent pen™ 2190 were found to be 0.78 and 0.83, respectively, to distinguish presence/absence of WSLs with good accuracy (AUC= 0.855; 95% CI: 0.820-0.889) and for digital photographs, accuracy was excellent (AUC= 0.973, 95% CI: 0.956-0.991) with sensitivity and specificity of 0.96 and 0.99, respectively. However, the accuracy of DIAGNOdent pen™ 2190 was poor (AUC= 0.543, 95% CI: 0.418-0.668) in delineating slight and severe WSLs with a sensitivity of 0.31 and specificity of 0.83; while the values of sensitivity and specificity for distinguishing slight or severe lesions for clinical photographs were 0.96 and 0.99, respectively with excellent accuracy (AUC=0.978, 95% CI: 0.936-1.000).
Clinical photographs had better validity than DIAGNOdent pen™ 2190 in diagnosis and assessment of severity of demineralized lesions during multi-bracketed fixed orthodontic treatment.
比较 DIAGNOdent pen™ 2190 与临床照片在多托槽固定正畸治疗中诊断(有无)和评估白垩斑(WSL)的有效性。
对 99 例患者的 1607 个读数进行 DIAGNOdent pen™ 2190、临床照片和视觉评估标准评估,以评估托槽粘结后 6、12 和 18 个月 WSL 的情况。构建受试者工作特征曲线,并计算曲线下面积(AUC),以评估 WSL 的存在或不存在以及区分 WSL 的严重程度为轻度或重度。计算敏感性、特异性和 AUC,结果以 0.05 和 95%置信区间(CI)的α值表示。
发现 DIAGNOdent pen™ 2190 区分 WSL 存在/不存在的敏感性和特异性分别为 0.78 和 0.83,具有较好的准确性(AUC=0.855;95%CI:0.820-0.889),数字照片的准确性为极好(AUC=0.973,95%CI:0.956-0.991),敏感性和特异性分别为 0.96 和 0.99。然而,DIAGNOdent pen™ 2190 区分轻度和重度 WSL 的准确性较差(AUC=0.543,95%CI:0.418-0.668),敏感性为 0.31,特异性为 0.83;而临床照片区分轻度或重度病变的敏感性和特异性分别为 0.96 和 0.99,准确性极好(AUC=0.978,95%CI:0.936-1.000)。
在多托槽固定正畸治疗中,临床照片在诊断和评估脱矿病变严重程度方面比 DIAGNOdent pen™ 2190 更有效。