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[影响新生儿胎记和皮肤病变发生发展的各种因素分析]

[Analysis of various factors influencing the development of birthmarks and cutaneous lesions in newborn infants].

作者信息

Ábrahám Rita, Gyurkovits Zita, Bakki Judit, Orvos Hajnalka, Kemény Lajos, Csoma Zsanett Renáta

机构信息

1 Szegedi Tudományegyetem, Általános Orvostudományi Kar, Bőrgyógyászati és Allergológiai Klinika Szeged, Korányi fasor 6., 6720 Magyarország.

2 Szegedi Tudományegyetem, Általános Orvostudományi Kar, Szülészeti és Nőgyógyászati Klinika Szeged Magyarország.

出版信息

Orv Hetil. 2022 Mar 27;163(13):513-522. doi: 10.1556/650.2022.32396.

DOI:10.1556/650.2022.32396
PMID:35339990
Abstract

Introduction: Cutaneous lesions are very frequent in neonates. Despite the fact that the incidence of neonatal skin disorders has been reported in several studies, very few reports address the factors that influence the appearance of birthmarks. Objective: In this cross-sectional study, we aimed to record cutaneous findings in essentially healthy, term and late preterm neonates, and to use this data to assess the associations between various factors and the appearance of birthmarks. Method: The study was conducted on consecutive neonates born between April 2014 and April 2015 at the Department of Obstetrics and Gynecology at the University of Szeged. After the whole-body skin examination, a standardized questionnaire consisting of 50 questions was completed by the mothers. Data relating to the neonatal history of the participating neonates were obtained from the official neonatal medical charts. Results: A total of 1629 Caucasian neonates were included in the study. Of these, 88.15% exhibited at least one skin manifestation. Significant correlations were found between the newborn gender, gestational age and weight and the presence of many skin manifestations. Furthermore, sociodemographic factors, parental phenotypic characteristics, maternal diseases and medicine-taking habits also have impact on the development of certain cutaneous lesions. Conclusion: By examining a large number of newborns and by providing detailed analysis of several neonatal, perinatal and parental factors, our study contributes to a deeper understanding of the development of the examined cutaneous lesions. Orv Hetil. 2022; 163(13): 513–522.

摘要

引言

皮肤病变在新生儿中非常常见。尽管多项研究报告了新生儿皮肤疾病的发病率,但很少有报告涉及影响胎记出现的因素。目的:在这项横断面研究中,我们旨在记录基本健康的足月儿和晚期早产儿的皮肤检查结果,并利用这些数据评估各种因素与胎记出现之间的关联。方法:该研究对2014年4月至2015年4月在塞格德大学妇产科出生的连续新生儿进行。在全身皮肤检查后,母亲们完成了一份由50个问题组成的标准化问卷。参与研究的新生儿的新生儿病史数据来自官方新生儿病历。结果:该研究共纳入1629名白人新生儿。其中,88.15%的新生儿至少有一处皮肤表现。新生儿的性别、胎龄和体重与多种皮肤表现的存在之间存在显著相关性。此外,社会人口学因素、父母的表型特征、母亲的疾病和用药习惯也对某些皮肤病变的发展有影响。结论:通过检查大量新生儿并对多种新生儿、围产期和父母因素进行详细分析,我们的研究有助于更深入地了解所检查的皮肤病变的发展。《匈牙利医学周报》。2022年;163(13):513–522。

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