Chiappini Emilio, Silani Giorgia, Korb Sebastian
Department of Clinical and Health Psychology, University of Vienna, Vienna, Austria.
Department of Cognition, Emotion, and Methods in Psychology, University of Vienna, Vienna, Austria.
Bio Protoc. 2022 Feb 20;12(4):e4325. doi: 10.21769/BioProtoc.4325.
Understanding the neural basis of reward processing is a major concern, as it holds the key to alleviating symptoms of addiction and poor mental health. However, this goal seems difficult to attain as long as research on reward processing cannot easily be compared across species and reward types, due to methodological differences and the presence of confounding factors. We recently developed an experimental paradigm that allows monitoring anticipatory and consummatory responses to matched social (touch) and nonsocial (food) rewards in adult humans. The following protocol describes in detail the materials and the paradigm, which measures reward wanting and liking with a real effort task and subjective ratings. It can also be used in combination with facial electromyography (EMG), brain imaging (., fMRI), and pharmacological interventions. It is our firm belief that the field will profit greatly from more research being conducted on reward processing using this and similarly controlled paradigms, which allow for cross-species comparison.
理解奖赏处理的神经基础是一个主要关注点，因为它是缓解成瘾症状和改善心理健康的关键。然而，只要由于方法学差异和混杂因素的存在，奖赏处理的研究难以在不同物种和奖赏类型之间进行轻松比较，这个目标似乎就难以实现。我们最近开发了一种实验范式，该范式能够监测成年人对匹配的社交（触摸）和非社交（食物）奖赏的预期和 consummatory 反应。以下方案详细描述了材料和范式，其通过实际努力任务和主观评分来测量对奖赏的渴望和喜好。它还可以与面部肌电图（EMG）、脑成像（如 fMRI）以及药物干预相结合使用。我们坚信，通过使用这种以及类似的受控范式对奖赏处理进行更多研究，该领域将受益匪浅，这些范式允许进行跨物种比较。
