Kerns L L
J Nerv Ment Dis. 1986 Nov;174(11):652-9. doi: 10.1097/00005053-198611000-00003.
Pregnancy can be complicated by affective or psychotic illnesses severe enough to threaten the health and life of both mother and fetus. In many cases, nonbiological interventions like psychotherapy or hospitalization in a supportive milieu will be insufficient, and use of a psychotropic drug will be indicated. This paper outlines the characteristics of maternal and fetal physiology that influence drug risks and then reviews the specific risks and benefits associated with antipsychotics, antidepressants, and lithium.
妊娠可能会并发严重到足以威胁母亲和胎儿健康及生命的情感性或精神性疾病。在许多情况下,心理治疗或在支持性环境中住院等非生物性干预措施并不足够,此时就需要使用精神药物。本文概述了影响药物风险的母体和胎儿生理学特征,然后回顾了与抗精神病药物、抗抑郁药物和锂相关的具体风险和益处。