Du Yihang, Duan Chenglin, Yang Yihan, Yuan Guozhen, Zhou Yan, Zhu Xueping, Wei Namin, Hu Yuanhui
Cardiovascular department, Guang'anmen Hospital, China Academy of Traditional Chinese Medicine Sciences, Beijing, China.
Cardiovascular department, Guang'anmen Hospital, China Academy of Traditional Chinese Medicine Sciences, Beijing, China; Beijing University of Chinese Medicine, Beijing, China.
Curr Probl Cardiol. 2022 Aug;47(8):101176. doi: 10.1016/j.cpcardiol.2022.101176. Epub 2022 Mar 24.
As the rapidly aging population and the rising incidence of end-stage heart failure, extensive research has been conducted on heart transplantation (HTx). Bibliometrics harbors the function for describing the relationships of knowledge structures in different research fields and predicting the growth trend. The publications were searched and filtered based on the Web of Science core database. The target literature was visualized and analyzed by CiteSpace or VOSviewer. In total, 19,998 published papers were obtained. There is a wave-like growth in HTx development. Most advanced research results are concentrated in a few developed countries, while the interactions with developing countries are still in infancy. The United States occupies a strong dominant position among active countries on HTx. Early research hotpots mostly focused on primary disease, survival risk factors, and complications. In recent years, the research frontiers have shifted steadily to clinical evaluation of immunosuppressants and diagnosis of acute rejection, cardiac re-injury with coronavirus disease 2019, innovations in ventricular assist devices, and donation allocation strategies. The research directions of HTx are gradually shifting from observational studies to intervention research.
随着人口的快速老龄化以及终末期心力衰竭发病率的上升，人们对心脏移植（HTx）进行了广泛的研究。文献计量学具有描述不同研究领域知识结构关系和预测发展趋势的功能。基于科学网核心数据库对出版物进行检索和筛选。通过CiteSpace或VOSviewer对目标文献进行可视化分析。共获得19998篇已发表论文。心脏移植的发展呈波浪式增长。大多数前沿研究成果集中在少数发达国家，而与发展中国家的互动仍处于起步阶段。美国在心脏移植活跃国家中占据强势主导地位。早期研究热点主要集中在原发性疾病、生存风险因素和并发症上。近年来，研究前沿已稳步转向免疫抑制剂的临床评估和急性排斥反应的诊断、2019冠状病毒病导致的心脏再损伤、心室辅助装置的创新以及捐赠分配策略。心脏移植的研究方向正逐渐从观察性研究转向干预性研究。
