Department of Sport and Exercise Science, College of Education, Zhejiang University, 886 Yuhangtang Road, Hangzhou 310058, China.
College of Computer Science and Technology, Zhejiang University, 886 Yuhangtang Road, Hangzhou 310058, China.
Int J Environ Res Public Health. 2020 Jul 28;17(15):5411. doi: 10.3390/ijerph17155411.
Research on chronic traumatic encephalopathy (CTE) has increased over the past two decades. However, few studies have statistically analyzed these publications. In this work, we conducted a bibliometric analysis of studies on CTE to track research trends and highlight current research hotspots. Relevant original articles were obtained from the Web of Science Core Collection database between 1999 and 2019. CiteSpace and VOSviewer software were used to perform analysis and visualization of scientific productivity and emerging trends. Our results show that the publications related to CTE dramatically increased from four publications in 1999 to 160 publications in 2019. The United States dominated this field with 732 publications (75.934%), followed by Canada with 88 publications (9.129%). Most of related publications were published in the journals with a focus on molecular biology, immunology, neurology, sports and ophthalmology, as represented by the dual-map overlay. A total of 11 major clusters were explored based on the reference co-citation analysis. In addition, three predominant research topics were summarized by clustering high-frequency keywords: epidemiological, clinical and pathological studies. The research frontiers were the diagnosis of diseases using new neuroimaging techniques, and the investigation of the molecular mechanism of tau aggregation. This study provides researchers with valuable guidance in the selection of research topics.
慢性创伤性脑病（CTE）的研究在过去二十年中有所增加。然而，很少有研究对这些出版物进行统计学分析。在这项工作中，我们对 CTE 的研究进行了文献计量分析，以跟踪研究趋势并突出当前的研究热点。相关的原始文章是从 1999 年至 2019 年的 Web of Science 核心合集数据库中获得的。使用 CiteSpace 和 VOSviewer 软件对科学生产力和新兴趋势进行分析和可视化。我们的结果表明，与 CTE 相关的出版物从 1999 年的 4 篇增加到 2019 年的 160 篇，增长幅度很大。美国以 732 篇（75.934%）的出版物主导了这一领域，其次是加拿大（9.129%），有 88 篇出版物。相关出版物主要发表在以分子生物学、免疫学、神经学、运动学和眼科学为重点的期刊上，这一点在双图叠加中得到了体现。通过参考文献共被引分析共探讨了 11 个主要聚类。此外，通过聚类高频关键词总结了三个主要的研究主题：流行病学、临床和病理学研究。研究前沿是使用新的神经影像学技术进行疾病诊断，以及对 tau 聚集的分子机制的研究。这项研究为研究人员在选择研究课题方面提供了有价值的指导。
