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百里香、甜橙、丁香花蕾和乳香的芳香疗法混合配方可提高新冠后女性患者的能量水平:一项随机、双盲、安慰剂对照的临床试验。

Aromatherapy blend of thyme, orange, clove bud, and frankincense boosts energy levels in post-COVID-19 female patients: A randomized, double-blinded, placebo controlled clinical trial.

机构信息

Franklin Health Research Center, 1650 Murfreesboro Rd., Ste 245, Franklin, TN 37067, United States.

Franklin Health Research Center, 1650 Murfreesboro Rd., Ste 245, Franklin, TN 37067, United States.

出版信息

Complement Ther Med. 2022 Aug;67:102823. doi: 10.1016/j.ctim.2022.102823. Epub 2022 Mar 25.

DOI:10.1016/j.ctim.2022.102823
PMID:35341944
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8949693/
Abstract

BACKGROUND

A large proportion of individuals who have recovered from an acute COVID-19 infection continue to experience symptoms months later. Post-acute COVID-19 (long-haul COVID-19) can range from serious complications to quality of life symptoms such as fatigue or insomnia. The purpose of this study was to evaluate the potential for inhalation of essential oils to improve energy levels among otherwise healthy female survivors of acute COVID-19 who experience a lack of energy more than five months after recovery. This study was conducted in the United States in late 2021.

METHOD

This was a randomized double blind, placebo controlled trial to evaluate the potential for inhalation of Longevity™, a proprietary essential oil blend manufactured by Young Living Essential Oils (Lehi, Utah, USA), on energy levels among female survivors of COVID-19 who continue to experience fatigue more than 5 months recovery from the acute infection. Forty women were randomized to two groups: intervention and placebo. Both groups inhaled the assigned product twice daily for fourteen consecutive days. Fatigue scores were measured using the Multidimensional Fatigue Symptom Inventory (MFSI). Secondary outcomes included scores on each of the MFSI's ten subscales.

RESULTS

Individuals who inhaled the essential oil blend for 2 weeks had significantly lower fatigue scores after controlling for baseline scores, employment status, BMI, olfactory function, and time since diagnosis, with a large effect size (F (1,39) = 6.15, p = .020, partial eta squared = 0.198). Subscale analysis identified subscales of vigor, as well as global, behavioral, general, and mental fatigue as benefiting from the intervention. This study provides evidence that a proprietary aromatherapy blend can significantly improve energy levels among women who are experiencing fatigue after recovering from COVID-19.

摘要

背景

很大一部分从急性 COVID-19 感染中康复的人在数月后仍会持续出现症状。COVID-19 后(post-acute COVID-19,简称“长新冠”)可出现从严重并发症到生活质量症状,如疲劳或失眠。本研究旨在评估吸入精油是否能改善急性 COVID-19 康复后 5 个月以上仍感到乏力的健康女性幸存者的能量水平。本研究于 2021 年末在美国进行。

方法

这是一项随机双盲、安慰剂对照试验,旨在评估吸入由 Young Living essential Oils(犹他州利希)生产的专有精油混合物 LongevityTM 对 COVID-19 女性幸存者能量水平的潜在影响,这些女性在急性感染康复 5 个月以上后仍持续感到疲劳。40 名女性被随机分为两组:干预组和安慰剂组。两组均连续 14 天每天吸入指定产品 2 次。疲劳评分采用多维疲劳症状清单(Multidimensional Fatigue Symptom Inventory,MFSI)进行测量。次要结局包括 MFSI 的 10 个分量表的评分。

结果

在控制基线评分、就业状况、体重指数、嗅觉功能和诊断后时间后,吸入精油混合物 2 周的个体疲劳评分显著降低,具有较大的效应量(F(1,39)=6.15,p=0.020,偏 eta 平方=0.198)。亚量表分析确定了活力以及整体、行为、一般和精神疲劳等亚量表受益于干预。本研究提供了证据,表明一种专有芳香疗法混合物可以显著改善从 COVID-19 康复后出现疲劳的女性的能量水平。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/074e/8949693/91edd4355a93/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/074e/8949693/91edd4355a93/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/074e/8949693/91edd4355a93/gr1_lrg.jpg

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