Department of Pediatrics, Wake Forest School of Medicine (CL Brown), Winston-Salem, NC; Department of Epidemiology and Prevention, Wake Forest School of Medicine (CL Brown), Winston-Salem, NC.
Department of Population Health Sciences, Duke University (AC Skinner), Durham, NC.
Acad Pediatr. 2022 Nov-Dec;22(8):1353-1359. doi: 10.1016/j.acap.2022.03.014. Epub 2022 Mar 24.
We evaluated the prevalence of high weight status in children ages 0 to 24 months (m) using data from electronic health records (EHR) and NHANES. We also examined relationships between weight status during infancy and obesity at 24 months of age.
EHR data from 4 institutions in North and South Carolina included patients born January 1, 2013-October 10, 2017 (N = 147,290). NHANES data included study waves from 1999 to 2018 (unweighted N = 5121). We calculated weight-for-length (WFL), weight-for-age (WFA), and body mass index (BMI), excluding implausible values, and categorized weight status (<85th, 85th to <95th, or ≥95th percentile), assessing prevalence at birth, 6, 12, 18, and 24 months. Utilizing individual, longitudinal EHR data, we used separate regression models to assess obesity risk at 24 months based on anthropometrics at birth, 6, 12, and 18 months, adjusting for sex, race/ethnicity, insurance, and health system.
Prevalence of BMI ≥95th percentile in EHR data at 6, 12, 18, and 24 months were 9.7%, 15.7%, 19.6%, and 20.5%, respectively. With NHANES the prevalence was 11.6%, 15.0%, 16.0%, and 8.4%. For both, the prevalence of high weight status was higher in Hispanic children. In EHR data, high weight status at 6, 12, and 18 months was associated with obesity at 24 months, with stronger associations as BMI category increased and as age increased.
High weight status is common in infants and young children, although lower at 24 months in NHANES than EHR data. In EHR data, high BMI at 6, 12, and 18 months was associated with increased risk of obesity at 24 months.
我们利用电子健康记录(EHR)和 NHANES 的数据评估了 0 至 24 个月(m)儿童超重的患病率。我们还研究了婴儿期体重状况与 24 个月时肥胖之间的关系。
北卡罗来纳州和南卡罗来纳州 4 家机构的 EHR 数据包括 2013 年 1 月 1 日至 2017 年 10 月 10 日出生的患者(N=147290)。NHANES 数据包括 1999 年至 2018 年的研究波(未加权 N=5121)。我们计算了体重-身长(WFL)、体重-年龄(WFA)和体重指数(BMI),排除了不合理的值,并根据出生、6、12、18 和 24 个月的体重状况将体重状况分类(<85th、85th 至<95th 或≥95th 百分位),评估了患病率。利用个体、纵向 EHR 数据,我们使用单独的回归模型,根据出生、6、12 和 18 个月的人体测量学数据,调整性别、种族/民族、保险和卫生系统,评估 24 个月时的肥胖风险。
EHR 数据中,6、12、18 和 24 个月时 BMI≥95 百分位的患病率分别为 9.7%、15.7%、19.6%和 20.5%。NHANES 的患病率分别为 11.6%、15.0%、16.0%和 8.4%。在这两个数据集中,西班牙裔儿童的高体重状况患病率更高。在 EHR 数据中,6、12 和 18 个月时的高体重状况与 24 个月时的肥胖有关,随着 BMI 类别增加和年龄增加,关联度更强。
超重状况在婴儿和幼儿中很常见,尽管 NHANES 数据中 24 个月时的患病率较低。在 EHR 数据中,6、12 和 18 个月时的高 BMI 与 24 个月时肥胖的风险增加有关。