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与没有精神疾病登记的人相比,患有精神疾病的人达到糖尿病治疗目标的情况相似或有所改善:基于相关观察性数据集的分析。

Achieving diabetes treatment targets in people with registered mental illness is similar or improved compared with those without: Analyses of linked observational datasets.

机构信息

Department of Public Health and Primary Care, LUMC-Campus The Hague, Leiden University Medical Centre, The Hague, The Netherlands.

National Institute for Public Health and the Environment, Bilthoven, The Netherlands.

出版信息

Diabet Med. 2022 Jun;39(6):e14835. doi: 10.1111/dme.14835. Epub 2022 Apr 1.

Abstract

AIMS

To determine the association between registered mental illness and type 2 diabetes mellitus treatment targets, while taking into account the effects of health expenditure and social determinants of health.

METHODS

This observational cross-sectional study was based on routine primary care data, linked to socio-economic and medical claims data. The main outcomes, analysed by multivariate logistic regression, were achieving primary care guideline treatment targets for HbA , systolic blood pressure (SBP) and LDL-cholesterol in 2017. We examined the association with diagnosed mental illness registered by the general practitioner (GP) or treated via specialist' mental healthcare between 2016 and 2018, adjusting for, medication use, body mass index, co-morbidity, smoking, and additionally examining effect-modification of healthcare expenditures, migration status, income and demographics.

RESULTS

Overall (N = 2862), 64.0% of participants achieved their treatment targets for HbA , 65.1% for SBP and 53.0% for LDL-cholesterol. Adjusted for migrant background, income and care expenditures, individuals <65 years of age with mental illness achieved their HbA treatment target more often than those without (OR (95% CI)): treatment by GP: 1.46 (1.01, 2.11), specialist care: 1.61 (1.11, 2.34), as did men with mental illness for SBP: GP OR 1.61 (1.09, 2.40), specialist care OR 1.59 (1.09, 2.45). LDL-cholesterol target was not associated with mental illness. A migrant background or low income lowered the likelihood of reaching HbA targets.

CONCLUSIONS

People with registered mental illness appear comparable or better able to achieve diabetes treatment targets than those without. Achieving HbA targets is influenced by social disadvantage.

摘要

目的

确定注册精神疾病与 2 型糖尿病治疗目标之间的关联,同时考虑健康支出和健康社会决定因素的影响。

方法

本观察性横断面研究基于常规初级保健数据,并与社会经济和医疗索赔数据相关联。主要结局通过多变量逻辑回归进行分析,即 2017 年达到 HbA、收缩压(SBP)和 LDL-胆固醇的初级保健指南治疗目标。我们检查了 2016 年至 2018 年期间全科医生(GP)登记或通过专科精神保健治疗的精神疾病诊断与治疗目标之间的关联,调整了药物使用、体重指数、合并症、吸烟,并进一步检查了医疗支出、移民身份、收入和人口统计学的影响修饰作用。

结果

总体(N=2862)中,64.0%的参与者达到了 HbA 的治疗目标,65.1%达到了 SBP 目标,53.0%达到了 LDL-胆固醇目标。调整移民背景、收入和护理支出后,<65 岁有精神疾病的个体比无精神疾病的个体更有可能达到 HbA 治疗目标(OR(95%CI)):由 GP 治疗:1.46(1.01,2.11),专科治疗:1.61(1.11,2.34),男性 GP 治疗 OR 1.61(1.09,2.40),专科治疗 OR 1.59(1.09,2.45)。LDL-胆固醇目标与精神疾病无关。移民背景或低收入降低了达到 HbA 目标的可能性。

结论

与没有精神疾病的个体相比,有注册精神疾病的个体似乎更能达到或更有能力达到糖尿病治疗目标。达到 HbA 目标受到社会劣势的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d38/9325400/11d7776bd4fc/DME-39-0-g003.jpg

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