Department of Otolaryngology, Children's Hospital of Chongqing Medical University, Chongqing, China.
National Clinical Research Center for Child Health and Disorders, Chongqing, China.
J Oral Rehabil. 2022 Jul;49(7):734-745. doi: 10.1111/joor.13325. Epub 2022 May 16.
The literature on oro-facial myofunctional therapy (OMT) in children and adults with obstructive sleep apnoea (OSA) was systematically reviewed to investigate the effects of OMT on patients with OSA by age and disease severity to verify the effect of OMT on OSA.
All the comparative literature was retrieved from the PubMed, Embase and Cochrane libraries.
We searched the articles published up to 12 February 2022 and followed the preferred reporting project for systematic review and meta-analysis of reports. The quality of the studies was evaluated using the Newcastle-Ottawa scale.
Of the primary indicators for evaluating OSA, 13 studies reported on the apnoea index (AHI), showing a decrease in the mean standard deviation of AHI from before OMT to after OMT (p < .00001). The lowest oxygen saturation was reported in nine studies, and the mean standard deviation of the lowest oxygen saturation increased from before to after OMT (p = .0009). Ten studies reported the Epworth Sleepiness Scale (ESS), indicating that the mean standard deviation of the ESS decreased from before to after OMT (p < .00001). The subgroup analysis showed that the AHI scores indicating mild and moderate OSA were significantly reduced, and the AHI scores indicating severe OSA also decreased, but this was not statistically significant. The lowest oxygen saturation increased obviously in patients with both mild and moderate and severe OSA. Of the secondary indicators of OSA, there was a statistically significant improvement in snoring intensity (p = .0002).
Oral and facial muscular function therapy can be used as a simple and non-invasive new technique to improve the AHI, minimum oxygen saturation, ESS, and snoring intensity in patients with mild and moderate OSA and the lowest oxygen saturation in patients with severe OSA.
系统评价口腔面部肌肉功能疗法（OMT）在儿童和成人阻塞性睡眠呼吸暂停（OSA）患者中的文献，通过年龄和疾病严重程度研究 OMT 对 OSA 患者的影响，以验证 OMT 对 OSA 的疗效。
所有比较文献均从 PubMed、Embase 和 Cochrane 图书馆中检索。
检索截至 2022 年 2 月 12 日发表的所有文献，并遵循系统评价和荟萃分析报告的首选报告项目。使用纽卡斯尔-渥太华量表评估研究质量。
在评估 OSA 的主要指标中，13 项研究报告了呼吸暂停指数（AHI），显示 OMT 前后 AHI 的平均值标准差降低（p<0.00001）。9 项研究报告了最低血氧饱和度，OMT 前后最低血氧饱和度的平均值标准差增加（p=0.0009）。10 项研究报告了 Epworth 嗜睡量表（ESS），表明 ESS 的平均值标准差从 OMT 前到 OMT 后降低（p<0.00001）。亚组分析表明，轻度和中度 OSA 的 AHI 评分显著降低，重度 OSA 的 AHI 评分也降低，但无统计学意义。轻度和中度以及重度 OSA 患者的最低血氧饱和度明显增加。OSA 的次要指标中，打鼾强度有统计学意义的改善（p=0.0002）。
口腔面部肌肉功能疗法可作为一种简单、非侵入性的新技术，改善轻度和中度 OSA 患者的 AHI、最低血氧饱和度、ESS 和打鼾强度，以及重度 OSA 患者的最低血氧饱和度。
