• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

孤立性脑转移瘤切除术后诊断出的直肠癌。

Rectal cancer diagnosed after resection of isolated brain metastasis.

作者信息

Tagayasu Yoshiyuki, Miyamoto Yuji, Sawayama Hiroshi, Ogawa Katsuhiro, Kato Rikako, Yoshida Naoya, Mukasa Akitake, Baba Hideo

机构信息

Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto, 860-8556, Japan.

Department of Neurosurgery, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto, 860-8556, Japan.

出版信息

Surg Case Rep. 2022 Mar 28;8(1):52. doi: 10.1186/s40792-022-01407-8.

DOI:10.1186/s40792-022-01407-8
PMID:35344111
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8960526/
Abstract

BACKGROUND

Brain metastasis of colorectal cancer is infrequent, and isolated brain metastases are more infrequent. Thus, when neurological symptoms, such as paralysis or disturbance of consciousness appear, there is a high probability that the cancer has spread to other organs.

CASE PRESENTATION

Here, we present a 64-year-old man with a progressive headache, decreased motivation, and aphasia who was diagnosed with a brain tumor in the left frontal region. He underwent a craniotomy, and the brain tumor was diagnosed as adenocarcinoma. We performed a colonoscopy and diagnosed rectal cancer without other distant metastases. After whole-brain radiotherapy (WBRT), low anterior resection for primary rectal tumor was performed using a robotic system. The patient was discharged in good condition and received postoperative adjuvant therapy for rectal cancer. He showed no signs of recurrence after 1 year of follow-up.

CONCLUSIONS

We described a rare case of rectal cancer that was diagnosed after resection of isolated brain metastasis. A good prognosis was achieved with surgery and WBRT.

摘要

背景

结直肠癌脑转移并不常见,孤立性脑转移更为罕见。因此,当出现诸如瘫痪或意识障碍等神经症状时,癌症扩散至其他器官的可能性很高。

病例介绍

在此,我们报告一名64岁男性,患有进行性头痛、动力减退和失语症,被诊断为左额叶脑肿瘤。他接受了开颅手术,脑肿瘤被诊断为腺癌。我们进行了结肠镜检查,诊断为直肠癌且无其他远处转移。在全脑放疗(WBRT)后,使用机器人系统对原发性直肠肿瘤进行了低位前切除术。患者出院时情况良好,并接受了直肠癌术后辅助治疗。随访1年后未出现复发迹象。

结论

我们描述了一例罕见的直肠癌病例,该病例在孤立性脑转移切除术后被诊断出来。通过手术和WBRT取得了良好的预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/660c/8960526/facbba050dd8/40792_2022_1407_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/660c/8960526/26d92c25978a/40792_2022_1407_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/660c/8960526/623802ffe469/40792_2022_1407_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/660c/8960526/facbba050dd8/40792_2022_1407_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/660c/8960526/26d92c25978a/40792_2022_1407_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/660c/8960526/623802ffe469/40792_2022_1407_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/660c/8960526/facbba050dd8/40792_2022_1407_Fig3_HTML.jpg

相似文献

1
Rectal cancer diagnosed after resection of isolated brain metastasis.孤立性脑转移瘤切除术后诊断出的直肠癌。
Surg Case Rep. 2022 Mar 28;8(1):52. doi: 10.1186/s40792-022-01407-8.
2
An isolated vaginal metastasis from rectal cancer: a case report.直肠癌阴道孤立转移 1 例报告
J Med Case Rep. 2024 May 2;18(1):233. doi: 10.1186/s13256-024-04501-7.
3
[A Case of Rectal Cancer Diagnosed Based on Brain Metastasis and Had a Long-Term Prognosis by Radical Resections].[一例基于脑转移诊断的直肠癌经根治性切除获得长期预后的病例]
Gan To Kagaku Ryoho. 2022 Feb;49(2):223-225.
4
[A Case of Brain Metastasis from Rectal Cancer with Synchronous Liver and Lung Metastases after Multimodality Treatment--A Case Report].[1例直肠癌脑转移伴同步肝肺转移多模态治疗后的病例报告]
Gan To Kagaku Ryoho. 2015 Nov;42(12):1608-10.
5
Presacral lymph node recurrence of rectal intramucosal adenocarcinoma after endoscopic mucosal resection: a case report.内镜黏膜下剥离术后直肠黏膜内腺癌骶前淋巴结复发:1例报告
Surg Case Rep. 2020 Apr 21;6(1):78. doi: 10.1186/s40792-020-00836-7.
6
Long-term survival after surgical resection of metachronous lung, brain and thyroid gland metastases from rectal cancer: A case report.直肠癌异时性肺、脑和甲状腺转移瘤手术切除后的长期生存:一例报告
Int J Surg Case Rep. 2021 Feb;79:318-322. doi: 10.1016/j.ijscr.2021.01.054. Epub 2021 Jan 19.
7
Management of newly diagnosed single brain metastasis using resection and permanent iodine-125 seeds without initial whole-brain radiotherapy: a two institution experience.使用手术切除和永久性碘-125粒子植入治疗新诊断的单发脑转移瘤而不进行初始全脑放疗:两家机构的经验。
Neurosurg Focus. 2007 Mar 15;22(3):E3. doi: 10.3171/foc.2007.22.3.4.
8
[Three Cases of Unresectable Colorectal Cancer Curatively Resected after Effective Chemotherapy].[三例不可切除的结直肠癌经有效化疗后实现根治性切除]
Gan To Kagaku Ryoho. 2019 Mar;46(3):567-569.
9
[A Case of Multiple Tumor Neurosurgery for Brain Metastasis of Colorectal Cancer].[1例结直肠癌脑转移的多肿瘤神经外科手术病例]
Gan To Kagaku Ryoho. 2018 Jan;45(1):133-135.
10
Management of single brain metastasis: a practice guideline.单脑转移瘤的治疗:实践指南。
Curr Oncol. 2007 Aug;14(4):131-43. doi: 10.3747/co.2007.129.

引用本文的文献

1
Colorectal cancer metastasis to the brainstem: A single case report.结直肠癌转移至脑干:一例病例报告。
Surg Neurol Int. 2025 Mar 28;16:101. doi: 10.25259/SNI_873_2024. eCollection 2025.
2
The Sigmoid Colon as an Unusual Primary Site of T Cell Lymphoma in a Patient Presenting With Brain Metastasis.一名出现脑转移的患者,其乙状结肠为T细胞淋巴瘤的罕见原发部位。
ACG Case Rep J. 2023 Oct 5;10(10):e01172. doi: 10.14309/crj.0000000000001172. eCollection 2023 Oct.
3
Machine learning algorithms to predict atypical metastasis of colorectal cancer patients after surgical resection.

本文引用的文献

1
Incidence of Asymptomatic Brain Metastases in Metastatic Colorectal Cancer.无症状脑转移在转移性结直肠癌中的发生率。
Clin Colorectal Cancer. 2020 Dec;19(4):263-269. doi: 10.1016/j.clcc.2020.09.002. Epub 2020 Sep 12.
2
Distribution Of Brain Metastasis From Lung Cancer.肺癌脑转移的分布
Cancer Manag Res. 2019 Nov 1;11:9331-9338. doi: 10.2147/CMAR.S222920. eCollection 2019.
3
Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2019 for the treatment of colorectal cancer.日本结直肠癌学会(JSCCR)2019 年结直肠癌治疗指南。
预测结直肠癌患者手术切除后非典型转移的机器学习算法。
Front Surg. 2023 Jan 6;9:1049933. doi: 10.3389/fsurg.2022.1049933. eCollection 2022.
Int J Clin Oncol. 2020 Jan;25(1):1-42. doi: 10.1007/s10147-019-01485-z. Epub 2019 Jun 15.
4
Brain metastases in colorectal cancer: prognostic factors and survival analysis.结直肠癌脑转移:预后因素与生存分析
Int J Colorectal Dis. 2018 Nov;33(11):1517-1523. doi: 10.1007/s00384-018-3107-6. Epub 2018 Jun 25.
5
Brain Metastasis from Colorectal Cancer: Predictors and Treatment Outcomes.结直肠癌脑转移:预测因素与治疗结果
Oncology. 2017;93(5):309-314. doi: 10.1159/000478661. Epub 2017 Jul 13.
6
Neurological symptoms from a brain metastasis as the first presentation of colorectal cancer.脑转移瘤所致神经症状作为结直肠癌的首发表现
BMJ Case Rep. 2015 Sep 22;2015:bcr2015210422. doi: 10.1136/bcr-2015-210422.
7
Brain metastases in colorectal cancers.结直肠癌的脑转移
World J Surg. 2009 Apr;33(4):817-21. doi: 10.1007/s00268-009-9919-3.
8
Changing patterns of bone and brain metastases in patients with colorectal cancer.结直肠癌患者骨转移和脑转移模式的变化
Clin Colorectal Cancer. 2005 Jul;5(2):108-13. doi: 10.3816/ccc.2005.n.022.
9
Incidence of brain metastases in a cohort of patients with carcinoma of the breast, colon, kidney, and lung and melanoma.一组乳腺癌、结肠癌、肾癌、肺癌患者及黑色素瘤患者中脑转移瘤的发病率。
Cancer. 2002 May 15;94(10):2698-705. doi: 10.1002/cncr.10541.
10
Brain metastases from colorectal carcinoma.结直肠癌脑转移
Tumori. 2001 Sep-Oct;87(5):332-4. doi: 10.1177/030089160108700511.