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[三例不可切除的结直肠癌经有效化疗后实现根治性切除]

[Three Cases of Unresectable Colorectal Cancer Curatively Resected after Effective Chemotherapy].

作者信息

Kinoshita Haruhito, Noda Eiji, Mori Takuya, Hasegawa Tsuyoshi, Teraoka Hitoshi, Hirakawa Kosei, Ohira Masaichi

机构信息

Dept. of Surgery, Baba Memorial Hospital.

出版信息

Gan To Kagaku Ryoho. 2019 Mar;46(3):567-569.

PMID:30914616
Abstract

Case 1: A60-year-old man underwent resection of a brain tumor, which was pathologically diagnosed as adenocarcinoma. As he was diagnosed with unresectable rectal cancer due to pulmonary metastasis, we performed abdominoperineal resection after chemotherapy. Since pulmonary metastasis and local recurrence were detected 1 year after the surgery, he was administered chemotherapy. He died 37 months after the surgery. Case 2: A6 4-year-old man was diagnosed with unresectable rectal cancer due to pulmonary and hepatic metastases, resulting in an examination for melena. We performed laparoscopic low anterior resection and hepatic partial resection after chemotherapy. No relapse has occurred 1 year after the surgery. Case 3: A39 -year-old man was examined for abdominal pain and distension and was diagnosed with unresectable rectal cancer due to invasion of the left ureter and multiple hepatic metastases. We performed anterior resection, hepatic partial resection, and RFAafter chemotherapy. He has remained in relapse-free survival for 15 months after the surgery. These results suggest that curative resection after chemotherapy improves the prognosis of unresectable colorectal cancer.

摘要

病例1:一名60岁男性接受了脑肿瘤切除术,病理诊断为腺癌。由于他因肺转移被诊断为无法切除的直肠癌,我们在化疗后进行了腹会阴联合切除术。术后1年发现肺转移和局部复发,遂给予化疗。术后37个月死亡。病例2:一名64岁男性因肺和肝转移被诊断为无法切除的直肠癌,因此接受了黑便检查。我们在化疗后进行了腹腔镜低位前切除术和肝部分切除术。术后1年未出现复发。病例3:一名39岁男性因腹痛和腹胀接受检查,因左输尿管侵犯和多发肝转移被诊断为无法切除的直肠癌。我们在化疗后进行了前切除术、肝部分切除术和射频消融术。术后他已无瘤生存15个月。这些结果表明,化疗后进行根治性切除可改善无法切除的结直肠癌的预后。

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