Department of Molecular Imaging Research, Kobe City Medical Center General Hospital, 2-1-1 Minatojima-Minamimachi, Chuo-ku, Kobe, 650-0047, Japan.
Department of Nuclear Medicine, Saitama Medical University International Medical Center, Hidaka, Japan.
Jpn J Radiol. 2022 Aug;40(8):755-767. doi: 10.1007/s11604-022-01264-3. Epub 2022 Mar 28.
Positron emission tomography (PET) using 2-deoxy-2-[F]fluoro-D-glucose ([F]FDG) is widely used in oncology and other fields. In [F]FDG PET images, increased muscle uptake is observed owing exercise load or muscle tension, in addition to malignant tumors and inflammation. Moreover, we occasionally observe non-pathological solitary or unilateral skeletal muscle uptake, which is difficult to explain the strict reason. In most cases, we can interpret them as not having pathological significance. However, it is important to recognize such muscle uptake patterns to avoid misdiagnoses with pathological ones. Therefore, the teaching point of this pictorial essay is to comprehend the patterns of solitary or asymmetrical skeletal muscle uptake seen in routine [F]FDG-PET scans. As an educational goal, you will be able to mention muscles where intense physiological [F]FDG uptake can be observed, differentiate between physiological muscle uptake and lesion, and discuss with any physicians or specialists about uncertain muscle uptake.
正电子发射断层扫描(PET)使用 2-脱氧-2-[F]氟-D-葡萄糖([F]FDG)在肿瘤学和其他领域得到广泛应用。在[F]FDG PET 图像中,除了恶性肿瘤和炎症外,还可以观察到由于运动负荷或肌肉紧张引起的肌肉摄取增加。此外,我们偶尔会观察到非病理性的孤立或单侧骨骼肌摄取,很难解释其严格的原因。在大多数情况下,我们可以解释为没有病理意义。然而,认识到这种肌肉摄取模式对于避免与病理性摄取模式的误诊非常重要。因此,本影像学文章的教学要点是理解在常规[F]FDG-PET 扫描中观察到的孤立或不对称骨骼肌摄取模式。作为一个教育目标,您将能够提到可以观察到强烈生理[F]FDG 摄取的肌肉,区分生理肌肉摄取和病变,并与任何医生或专家讨论不确定的肌肉摄取。