Santone Elizabeth, Izzo Francesca, Lo Karina, Pérez Coulter Aixa M, Jabbour Nicolas, Orthopoulos Georgios
Department of Surgery, University of Massachusetts Chan Medical School-Baystate Medical Center, 759 Chestnut St, Springfield, MA 01199, USA.
Surg Open Sci. 2022 Jul;9:1-6. doi: 10.1016/j.sopen.2022.03.005. Epub 2022 Mar 24.
Acute appendicitis cases increased in severity following COVID-19-related restrictions in March, 2020. We investigated if similar changes occurred during Wave 2.
Acute appendicitis patients during Wave 1 were grouped 8 weeks before (Group A) and after (Group B) stay-at-home restrictions were initiated on March 15, 2020. Cases in Wave 2 were grouped 8 weeks before (Group C) and after (Group D) November 6, 2020. Groups were compared to equivalent time frames in 2018/2019.
Group A versus B revealed 42.6% decrease (confidence interval: - 59.4 to - 25.7) in uncomplicated appendicitis and 21.1% increase (confidence interval: 4.8-37.3) in perforated appendicitis. Similar patterns were noted comparing Group C versus D without statistical significance. The changes seen in Wave 1 were significantly different than in 2018/2019. This trend continued in Wave 2.
Similar to Wave 1, acute appendicitis cases increased in severity during wave 2 of COVID-19, but with less prominence.
2020年3月与COVID-19相关的限制措施实施后，急性阑尾炎病例的严重程度有所增加。我们调查了在第二波疫情期间是否发生了类似变化。
将第一波疫情期间的急性阑尾炎患者分为两组，一组为2020年3月15日开始居家限制措施前8周（A组），另一组为措施实施后8周（B组）。第二波疫情期间的病例分为2020年11月6日前8周（C组）和之后8周（D组）。将这些组与2018/2019年的相同时间框架进行比较。
A组与B组相比，单纯性阑尾炎减少了42.6%（置信区间：-59.4至-25.7），穿孔性阑尾炎增加了21.1%（置信区间：4.8-37.3）。C组与D组比较发现了类似模式，但无统计学意义。第一波疫情中出现的变化与2018/2019年有显著差异。这一趋势在第二波疫情中持续存在。
与第一波疫情类似，COVID-19第二波疫情期间急性阑尾炎病例的严重程度有所增加，但程度较轻。
