Subaxial lordosis loss and influence factors after posterior atlantoaxial fusion.

UNLABELLED

Cervical sagittal balance is an important evaluation index of cervical physiological function and surgical efficacy. Subaxial kyphosis after atlantoaxial fusion is negatively associated with worse clinical outcomes and higher incidence of lower cervical disk degeneration.

OBJECTIVES

This study aimed to confirm the factors that influence subaxial lordosis loss after posterior atlantoaxial fusion.

METHODS

We performed a retrospective review of all patients following posterior C1-C2 fusion for atlantoaxial dislocation between January 2015 and December 2017. All charts, records, and imaging studies were reviewed for each case, and preoperative, immediate postoperative, and final follow-up plain films were evaluated. Comparing final follow-up and preoperative C2-C7 angle, patients were divided into two groups for further comparison: subaxial lordosis loss group and subaxial lordosis increase group.

RESULTS

A total of 18 patients were included in the review, with an average radiographic follow-up of 8.4 ± 3.7 months (range 6-17 months). Subaxial lordosis loss was observed in 5 cases (27.8%) at the final follow-up, whereas 13 cases had an increase in subaxial lordosis. The cervical sagittal parameters of preoperative and final follow-up between two groups were compared, the preoperative C2-C7 angle of the subaxial lordosis loss group was bigger than the subaxial lordosis increase group (27.6° ± 10.5° vs 10.5° ± 10.5°, P < 0.05), but there was no statistical difference in other parameters. Univariate chi-square analysis showed that reduction in subaxial lordosis after posterior atlantoaxial fusion was associated with preoperative C2-C7 angle ≥ 20° (χ = 4.923, P = 0.026). However, Logistic regression analysis showed that the preoperative C2-C7 angle ≥ 20° was not an independent risk factor (OR = 0.147, P = 0.225).

CONCLUSION

Our study demonstrates that subaxial lordosis loss may occur after posterior atlantoaxial fusion, and preoperative C2-C7 angle ≥ 20° was a risk factor of postoperative loss of subaxial lordosis.