Department of Neurological Surgery, Mayo Clinic, 5777 East Mayo Blvd, Phoenix, AZ 85054, USA; Precision Neuro-therapeutics Innovation Lab, Mayo Clinic, Phoenix, AZ, USA; Neurosurgery Simulation and Innovation Lab, Mayo Clinic, Phoenix, AZ, USA.
Department of Neurology, Mayo Clinic, 5777 East Mayo Blvd, Phoenix, AZ 85054, USA.
Neurosurg Clin N Am. 2022 Apr;33(2):169-183. doi: 10.1016/j.nec.2021.12.001. Epub 2022 Mar 2.
Acute ischemic stroke continues to be a major cause of death and disability globally. Although the concept of endovascular treatment of ischemic stroke is relatively new, current evidence from high-quality randomized trials suggests a significant improvement in the clinical outcome with mechanical thrombectomy up to 24 hours from the stroke onset. There has been a paradigm shift from medical management to mechanical thrombectomy which is now considered standard of care in eligible patients. Not surprisingly, there has been a constant effort to further improve stroke care in the last few years with a common goal of ultra-rapid intervention along with highly effective revascularization methods. Currently, it is one of the most dynamic and rapidly changing subspecialties in the field of medicine with significant advances in all aspects of acute stroke treatment starting from triage in the field to poststroke rehabilitation.
急性缺血性脑卒中仍然是全球范围内主要的致死和致残病因。尽管血管内治疗缺血性脑卒中的理念相对较新，但目前高质量随机试验的证据表明，在脑卒中发病 24 小时内进行机械取栓可显著改善临床结局。从药物治疗到机械取栓的范式转变已经发生，机械取栓现在被认为是适合患者的标准治疗方法。毫不奇怪，在过去几年中，人们一直努力进一步改善脑卒中的治疗，其共同目标是实现超快速干预和高效的血管再通方法。目前，它是医学领域中最具活力和变化最快的亚专科之一，从现场分诊到脑卒中后康复，急性脑卒中治疗的各个方面都取得了显著进展。
