Syrvatka Vasyl, Rabets Andrii, Gromyko Oleksandr, Luzhetskyy Andriy, Fedorenko Victor
Genetics and Biotechnology Department, Ivan Franko National University of Lviv, Lviv, Ukraine.
Department of Pharmacy, Pharmaceutical Biotechnology, Saarland University, Saarbrücken, Germany.
Trends Biotechnol. 2022 Sep;40(9):1088-1101. doi: 10.1016/j.tibtech.2022.02.006. Epub 2022 Mar 25.
Scandium (Sc) plays a special role in high-tech industries because of its wide application in green, space, and defense technologies. However, Sc mining and purification are problematic due to political, technological, and environmental difficulties. The deficit of this element limits global technological development. One sustainable solution to this problem is to use microorganisms to extract Sc from ore and waste, as well as to concentrate and separate it from other elements. Sc also demonstrates attractive metabolic effects on microbes that is of great interest in white biotechnology. Sc increases the production of proteins and secondary metabolites and activates poorly expressed genes. This review offers a comprehensive analysis of current knowledge on the application of Sc-microorganism interactions in promising biotechnologies, its perspectives, and future challenges.
钪（Sc）在高科技产业中发挥着特殊作用，因为它在绿色、太空和国防技术中有着广泛应用。然而，由于政治、技术和环境方面的困难，钪的开采和提纯存在问题。这种元素的短缺限制了全球技术发展。解决这一问题的一个可持续办法是利用微生物从矿石和废料中提取钪，并将其与其他元素进行浓缩和分离。钪对微生物也表现出有吸引力的代谢作用，这在白色生物技术中引起了极大兴趣。钪能增加蛋白质和次生代谢产物的产量，并激活低表达基因。本综述全面分析了目前关于钪与微生物相互作用在有前景的生物技术中的应用、其前景及未来挑战的知识。
