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青少年和年轻成年人在精神病院住院治疗后的 3 年内的自伤、躯体障碍和死亡率。

Self-harm, somatic disorders and mortality in the 3 years following a hospitalisation in psychiatry in adolescents and young adults.

机构信息

Department of psychiatry, Jena University Hospital, Jena, Germany

Department of psychiatry, Academic Hospital (CHU) Nîmes, Nîmes, France.

出版信息

Evid Based Ment Health. 2022 Nov;25(4):177-184. doi: 10.1136/ebmental-2021-300409. Epub 2022 Mar 28.

Abstract

BACKGROUND

There is limited recent information regarding the risk of self-harm, somatic disorders and premature mortality following discharge from psychiatric hospital in young people.

OBJECTIVE

To measure these risks in young people discharged from a psychiatric hospital as compared with both non-affected controls and non-hospitalised affected controls.

METHODS

Data were extracted from the French national health records. Cases were compared with two control groups.

CASES

all individuals aged 12-24 years, hospitalised in psychiatry in France in 2013-2014. Non-affected controls: matched for age and sex with cases, not hospitalised in psychiatry and no identification of a mental disorder in 2008-2014. Affected controls: unmatched youths identified with a mental disorder between 2008 and 2014, never hospitalised in psychiatry. Follow-up of 3 years. Logistic regression analyses were conducted with these confounding variables: age, sex, past hospitalisation for self-harm, past somatic disorder diagnosis.

FINDINGS

The studied population comprised 73 300 hospitalised patients (53.6% males), 219 900 non-affected controls and 9 683 affected controls. All rates and adjusted risks were increased in hospitalised patients versus both non-affected and affected controls regarding a subsequent hospitalisation for self-harm (HR=105.5, 95% CIs (89.5 to 124.4) and HR=1.5, 95% CI (1.4 to 1.6)), a somatic disorder diagnosis (HR=4.1, 95% CI (3.9-4.1) and HR=1.4, 95% CI (1.3-1.5)), all-cause mortality (HR=13.3, 95% CI (10.6-16.7) and HR=2.2, 95% CI (1.5-3.0)) and suicide (HR=9.2, 95% CI (4.3-19.8) and HR=1.7, 95% CI (1.0-2.9)).

CONCLUSIONS

The first 3 years following psychiatric hospital admission of young people is a period of high risk for self-harm, somatic disorders and premature mortality.

CLINICAL IMPLICATIONS

Attention to these negative outcomes urgently needs to be incorporated in aftercare policies.

摘要

背景

最近有关年轻人从精神病院出院后自残、躯体障碍和过早死亡风险的信息有限。

目的

与非患病对照和非住院患病对照相比,测量从精神病院出院的年轻人的这些风险。

方法

从法国国家健康记录中提取数据。病例与两组对照组进行比较。

病例

2013-2014 年在法国精神病院住院的 12-24 岁人群。非患病对照:与病例年龄和性别相匹配,2008-2014 年未在精神病院住院,且未确诊精神障碍。患病对照:2008 年至 2014 年间未在精神病院住院的患有精神障碍的未匹配青年。随访 3 年。使用这些混杂变量进行逻辑回归分析:年龄、性别、既往自残住院史、既往躯体障碍诊断。

结果

研究人群包括 73300 名住院患者(53.6%为男性)、219900 名非患病对照和 9683 名患病对照。与非患病和患病对照相比,所有住院患者的后续自残(HR=105.5,95%CI(89.5 至 124.4)和 HR=1.5,95%CI(1.4 至 1.6))、躯体障碍诊断(HR=4.1,95%CI(3.9-4.1)和 HR=1.4,95%CI(1.3-1.5))、全因死亡率(HR=13.3,95%CI(10.6-16.7)和 HR=2.2,95%CI(1.5-3.0))和自杀(HR=9.2,95%CI(4.3-19.8)和 HR=1.7,95%CI(1.0-2.9))的住院率均较高。

结论

年轻人从精神病院出院后的头 3 年是自残、躯体障碍和过早死亡的高风险期。

临床意义

迫切需要将这些不良后果纳入康复后政策中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fee7/10231439/f3b6db46dd43/ebmental-2021-300409f01.jpg

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