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脊髓损伤患者心理健康与自杀念头的全国性调查。

National survey of mental health and suicidal thoughts in people with spinal cord injury.

作者信息

Sanguinetti Rafael D, Soriano Jan Elaine, Squair Jordan W, Cragg Jacquelyn J, Larkin-Kaiser Kelly A, McGirr Alexander, Phillips Aaron A

机构信息

Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.

Departments of Physiology and Pharmacology Cardiac Sciences & Clinical Neurosciences, Libin Cardiovascular Institute of Alberta, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada.

出版信息

Spinal Cord. 2022 May;60(5):444-450. doi: 10.1038/s41393-022-00783-0. Epub 2022 Mar 28.

DOI:10.1038/s41393-022-00783-0
PMID:35347266
Abstract

STUDY DESIGN

Retrospective cross-sectional epidemiological study.

OBJECTIVES

Previous studies have quantified longitudinal psychological morbidity in individuals with spinal cord injury (SCI) relative to uninjured individuals. However, there is limited information regarding how lifestyle and socioeconomic factors are associated with mental health conditions in individuals with SCI. This study aims to quantify and compare mental health and suicidal thoughts in people with and without SCI, and examine the associations between mental health, suicidal thoughts, sex, age, lifestyle, and socioeconomic factors.

SETTING

Canada.

METHODS

The 2010 Canadian Community Health Survey (n > 40,000) was used, which includes several measures assessing mental health and suicidal thoughts. Bivariate and multivariate logistic regressions were performed and odds ratios with corresponding 95% confidence intervals were estimated. Sensitivity analyses were performed to evaluate the effect of covariates on reported effect sizes.

RESULTS

People with SCI had higher odds of having mood (3.6) and anxiety disorders (2.5), suicidal thoughts (2.3), self-perceived stress (1.9), and depression (4.4); in addition to lower odds of having good self-perceived mental health (0.24) and satisfaction with life (0.25). These differences persisted after adjusting for age, sex, lifestyle, and socioeconomic factors. Lower household income, fruit and vegetable consumption, and physical activity levels, and increased smoking use were associated with poorer mental health in individuals with SCI.

CONCLUSIONS

Mental health is poorer in those with SCI when compared with the general population. Those with SCI exhibit a unique profile of lifestyle and socioeconomic factors that are associated with poorer mental health and increased suicidal thoughts.

摘要

研究设计

回顾性横断面流行病学研究。

目的

以往研究已对脊髓损伤(SCI)个体相对于未受伤个体的纵向心理发病率进行了量化。然而,关于生活方式和社会经济因素如何与SCI个体的心理健康状况相关的信息有限。本研究旨在量化和比较有无SCI人群的心理健康状况和自杀念头,并研究心理健康、自杀念头、性别、年龄、生活方式和社会经济因素之间的关联。

地点

加拿大。

方法

使用了2010年加拿大社区健康调查(n>40000),其中包括多项评估心理健康和自杀念头的指标。进行了双变量和多变量逻辑回归,并估计了相应的95%置信区间的比值比。进行了敏感性分析以评估协变量对报告效应大小的影响。

结果

SCI患者出现情绪障碍(比值比3.6)、焦虑症(比值比2.5)、自杀念头(比值比2.3)、自我感知压力(比值比1.9)和抑郁症(比值比4.4)的几率更高;此外,自我感知心理健康状况良好(比值比0.24)和生活满意度高(比值比0.25)的几率更低。在调整年龄、性别、生活方式和社会经济因素后,这些差异仍然存在。家庭收入较低、水果和蔬菜摄入量较少、身体活动水平较低以及吸烟量增加与SCI个体心理健康状况较差有关。

结论

与普通人群相比,SCI患者的心理健康状况较差。SCI患者呈现出与较差心理健康状况和自杀念头增加相关的独特生活方式和社会经济因素特征。

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本文引用的文献

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A descriptive study of the prevalence of psychological distress and mental disorders in the Canadian population: comparison between low-income and non-low-income populations.加拿大人群心理困扰和精神障碍患病率的描述性研究:低收入人群与非低收入人群的比较。
Chronic Dis Can. 2010 Jun;30(3):84-94.
脊髓损伤患者自杀倾向的危险因素:关注身体和功能特征。
Ann Rehabil Med. 2023 Oct;47(5):377-384. doi: 10.5535/arm.23110. Epub 2023 Oct 4.
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Chronic stress hinders sensory axon regeneration via impairing mitochondrial cristae and OXPHOS.慢性应激通过损害线粒体嵴和氧化磷酸化来阻碍感觉轴突再生。
Sci Adv. 2023 Oct 6;9(40):eadh0183. doi: 10.1126/sciadv.adh0183.