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[普通医疗实践中的尿路感染。临床发现、致病微生物种类分布及其对16种抗生素敏感性的研究]

[Urinary tract infections in general medical practice. A study of clinical findings, of the distribution of causative microbial species and their sensitivity to 16 antibiotics].

作者信息

Lecomte F, Grise G, Morel A, Lemeland J F

出版信息

Pathol Biol (Paris). 1986 May;34(5):483-9.

PMID:3534727
Abstract

From April to July 1984, all of the strains recovered by 10 private laboratories in Upper-Normandy region (France) from urine samples from outpatients seen in office practices (public and private hospitals excluded) were preserved. A total of 829 strains were collected, identified and tested against antibiotics using disk diffusion techniques. These investigations, together with a synthesis of clinical findings, were carried out by the Laboratory of Bacteriology of the Rouen University Hospital. 78.1% of patients were females; all age groups were represented with a greater prevalence of subjects aged 26 to 35 and above 66. E. coli was the most prevalent pathogen (74.5% of all strains), followed by Proteus and Providencia (10%). E. coli was recovered in 78% of first infections against 67.7% of recurrent infections and 50% of prostatitis. More than 25% of strains were resistant to ampicillin; norfloxacin showed the best activity, with 96.5% of susceptible strains.

摘要

1984年4月至7月,诺曼底大区(法国)10家私人实验室从门诊患者(不包括公立医院和私立医院)的尿液样本中分离出的所有菌株均被保存。共收集了829株菌株,采用纸片扩散法进行鉴定和抗生素敏感性测试。这些研究以及临床结果的综合分析由鲁昂大学医院细菌学实验室完成。78.1%的患者为女性;各年龄组均有分布,其中26至35岁以及66岁以上的人群患病率较高。大肠杆菌是最常见的病原体(占所有菌株的74.5%),其次是变形杆菌和普罗威登斯菌(10%)。在首次感染中,大肠杆菌的检出率为78%,而复发性感染和前列腺炎中的检出率分别为67.7%和50%。超过25%的菌株对氨苄西林耐药;诺氟沙星表现出最佳活性,敏感菌株占96.5%。

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