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[尿路感染的致病原及对抗生素的敏感性]

[Causative agents of urinary tract infections and sensitivity to antibiotics].

作者信息

Ayhan N, Başbuğ N, Oztürk S

机构信息

Ankara Universitesi, Diş Hekimliği Fakültesi, Mikrobiyoloji Bilim Dali Araştirma Görevlisi.

出版信息

Mikrobiyol Bul. 1988;22(3):215-21.

PMID:3252113
Abstract

Our study was done on the outpatients and inpatients of Ankara Numune Hospital who were diagnosed as having urinary tract infections. When 301 cultures with positive results were evaluated. Gram-negative bacteria were found most frequently (E. coli 45.2%, Klebsiella 23.2%, Enterobacter 16.6%, Proteus 11.5%, S. aureus 2.2%, Pseudomonas 1.3%). By using the disc diffusion method, the effectiveness of antibiotic discs of amikacin, tobramycin, netilmycin, cephoperazone, cephotoxime, cephtizoxime, cephradine, cephuroxime, carbenicillin, piperacillin, ofloxacin, nalidixic acid and sulbactam/ampicillin on the isolated strains were investigated. Ofloxacin (92.35%), cephotaxime (72.6%) and nalidixic acid (62.10%) were found to be the most effective while cephradine (7.96%), carbenicillin (11.8%) and piperacillin (14.96%) were found to be the least effective antibiotics.

摘要

我们的研究针对安卡拉努穆内医院被诊断患有尿路感染的门诊和住院患者展开。对301份培养结果呈阳性的样本进行评估时,发现革兰氏阴性菌最为常见(大肠杆菌45.2%、克雷伯菌23.2%、肠杆菌16.6%、变形杆菌11.5%、金黄色葡萄球菌2.2%、铜绿假单胞菌1.3%)。采用纸片扩散法,研究了阿米卡星、妥布霉素、奈替米星、头孢哌酮、头孢噻肟、头孢唑肟、头孢拉定、头孢呋辛、羧苄西林、哌拉西林、氧氟沙星、萘啶酸和舒巴坦/氨苄西林等抗生素纸片对分离菌株的有效性。结果发现,氧氟沙星(92.35%)、头孢噻肟(72.6%)和萘啶酸(62.10%)最为有效,而头孢拉定(7.96%)、羧苄西林(11.8%)和哌拉西林(14.96%)则是最无效的抗生素。

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