Stahl J P, Leclercq P, Croize J, Lefebvre M A, Bru J P, Fourtillan J B, Le Noc P, Micoud M
Pathol Biol (Paris). 1986 May;34(5):505-7.
Nine patients with typhoid fever were given ofloxacin in a daily dosage of 400 mg for ten days. All patients recovered with no relapses. No case of Salmonella typhi carriage was recorded. Diffusion of ofloxacin into mesenteric lymph nodes was studied in four patients. Mean concentration was 1.46 micrograms/g after four 200 mg doses. According to our results, ofloxacin could be considered as one of the alternatives for treating typhoid fever.
9例伤寒患者接受氧氟沙星治疗，每日剂量400mg，疗程10天。所有患者均康复，无复发。未记录到伤寒杆菌带菌病例。对4例患者研究了氧氟沙星在肠系膜淋巴结中的扩散情况。4次给予200mg剂量后，平均浓度为1.46微克/克。根据我们的结果，氧氟沙星可被视为治疗伤寒的替代药物之一。
