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腰椎管狭窄症的骶尾部硬膜外注射:非影像、超声和透视引导技术的比较。一项随机临床试验。

Caudal Epidural Injections in Lumbar Spinal Stenosis: Comparison of Nonimage, Ultrasonography-, and Fluoroscopy-Guided Techniques. A Randomized Clinical Trial.

机构信息

Orthopaedic Department, Papageorgiou General Hospital of Thessaloniki, Thessaloniki, Greece.

出版信息

Perm J. 2021 Jun 9;25:20.321. doi: 10.7812/TPP/20.321.

DOI:10.7812/TPP/20.321
PMID:35348084
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8784067/
Abstract

INTRODUCTION

Caudal epidural injections (CEIs) are widely used in the treatment of lumbar spinal stenosis (LSS). Imaging modalities, such as fluoroscopy and ultrasonography, are frequently employed to confirm proper needle placement and to prevent possible complications. This is a prospective, randomized, study aiming to compare the efficacy of nonimage, ultrasonography-, and fluoroscopy-guided CEIs for the management of LSS.

METHODS

A total of 45 patients were included based on their clinical symptoms and their magnetic resonance images indicative of LSS. Patients were randomized and allocated into 3 equal groups, the nonimage, the ultrasonography-guided, and the fluoroscopy-guided group. All patients received 12 mg betamethasone and 4 mg ropivacaine dissolved in 20 mL normal saline. The injections were administered twice, with a 30-day interval. Visual Analogue Scale (VAS) and Oswestry Disability Index were recorded before the injections and 1 month after the second injection. The procedure times for each group were also compared.

RESULTS

Visual Analogue Scale scores and Oswestry Disability Index values were improved in all the groups compared to the baseline values (p < 0.001). The intergroup difference in Visual Analogue Scale scores and Oswestry Disability Index values before and after CEIs was not statistically significant (p = 0.836 and p = 0.438, respectively). The mean procedure time was higher for the fluoroscopy-guided group, followed by ultrasonography-guided, but the differences were not statistically significant (p = 0.067).

CONCLUSION

CEIs are an effective analgesic method for patients suffering from LSS. Nonimage, ultrasonography-, and fluoroscopy-guided CEIs are similarly effective in terms of pain relief and functional improvement.

摘要

简介

尾侧硬膜外注射(CEI)广泛应用于腰椎管狭窄症(LSS)的治疗。为了确认正确的针位并防止可能的并发症,通常采用影像学方法,如透视和超声。本研究旨在比较非影像、超声和透视引导 CEI 治疗 LSS 的疗效,这是一项前瞻性、随机研究。

方法

根据临床症状和磁共振成像(MRI)显示的 LSS,共纳入 45 名患者。患者随机分为 3 组,即非影像组、超声引导组和透视引导组。所有患者均接受 12mg 倍他米松和 4mg 罗哌卡因溶于 20mL 生理盐水。注射分两次进行,间隔 30 天。在注射前和第二次注射后 1 个月,记录视觉模拟量表(VAS)和 Oswestry 残疾指数(ODI)。还比较了每组的操作时间。

结果

与基线相比,所有组的 VAS 评分和 ODI 值均得到改善(p<0.001)。CEI 前后组间 VAS 评分和 ODI 值的差异无统计学意义(分别为 p=0.836 和 p=0.438)。透视引导组的平均操作时间最高,其次是超声引导组,但差异无统计学意义(p=0.067)。

结论

CEI 是治疗 LSS 患者的有效镇痛方法。非影像、超声和透视引导 CEI 在缓解疼痛和改善功能方面同样有效。

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