Department of Chemistry, Indian Institute of Technology Ropar, Nangal Road, Rupnagar, Punjab-140001, India.
Chem Commun (Camb). 2022 Apr 14;58(31):4857-4860. doi: 10.1039/d2cc00163b.
A method for generating alkyl radicals using visible-light photoredox catalysis is described. This procedure was found to present an efficient means to access a diverse collection of 1°, 2°, and 3° alkyl radicals through the single-electron transfer of sulfones under mild reaction conditions. These alkyl radicals generated the reductive desulfonylation of readily synthesized and stable alkylsulfones were engaged to forge C-C bonds. A detailed study was also carried out to shed light on the mechanism.
本文描述了一种利用可见光光氧化还原催化生成烷基自由基的方法。该方法通过亚砜的单电子转移，在温和的反应条件下，有效地实现了 1°、2°和 3°烷基自由基的多样化构建。所生成的烷基自由基可还原脱磺，而易于合成且稳定的烷基砜则可参与 C-C 键的形成。此外，还进行了详细的机理研究。
