Department of Dermatology and Venereology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.
Dermatology, Department of Medicine, College of Medicine, Shaqra University, Dawadmi, Saudi Arabia.
J Cosmet Dermatol. 2022 Oct;21(10):4659-4668. doi: 10.1111/jocd.14944. Epub 2022 Apr 9.
Atrophic acne scarring is an unfortunate, permanent complication of acne vulgaris, associated with significant psychological distress.
A new complementary treatment of atrophic acne scars using subcision and injection of hybrid cooperative complexes of high and low molecular weight hyaluronan (hybrid H-HA/L-HA).
This study included eighty-two patients divided into two groups with predominantly atrophic acne scarring. Group 1 received subcision with saline injection, while group 2 received triple steps acne scar revision technique (TSASRT). After topical anesthesia, the procedure of combining subcision and hybrid H-HA/L-HA technique was done in which the first step started using subcision technique done to release fibrous cords at the dermal or deep dermal, subcutaneous plane using Nokor needles-18 g. The second step is to inject the scar's atrophic dermal component with a 29 g needle, applying an average amount of hybrid H-HA/L-HA (0.02-0.1 mL) to the dermal component. The third step was to fill the subcisied space with hybrid H-HA/L-HA (0.02-0.1 mL) using a 25 g cannula.
Clinical improvement was achieved in both groups. There were statistically significant improvements in the TSASRT versus subcision (p ≤ 0.05) in acne scar severity index and qualitative scarring grading system.
The triple step acne scar revision technique appears to be a safe and effective way to treat atrophic acne scars on the face.
萎缩性痤疮瘢痕是寻常痤疮的一种不幸的永久性并发症,与明显的心理困扰有关。
使用低分子和高分子透明质酸(混合 H-HA/L-HA)的协同复合注射剂进行皮下分离术,为治疗萎缩性痤疮瘢痕提供一种新的补充疗法。
本研究纳入 82 例以萎缩性痤疮瘢痕为主的患者,分为两组。第 1 组接受盐水注射的皮下分离术,第 2 组接受三重痤疮瘢痕修正技术(TSASRT)。局部麻醉后,采用皮下分离术联合混合 H-HA/L-HA 技术,首先使用 Nokor 针-18G 在真皮或真皮深层皮下平面进行皮下分离术,以释放纤维索。第二步是用 29G 针将瘢痕的萎缩真皮成分注射,向真皮成分中注射平均量的混合 H-HA/L-HA(0.02-0.1mL)。第三步是用 25G 套管向皮下分离术的空间内填充混合 H-HA/L-HA(0.02-0.1mL)。
两组均获得临床改善。在痤疮瘢痕严重指数和定性瘢痕分级系统方面,TSASRT 与皮下分离术相比均有统计学显著改善(p≤0.05)。
三重痤疮瘢痕修正技术似乎是一种安全有效的治疗面部萎缩性痤疮瘢痕的方法。