Tamura J, Waki S
Z Parasitenkd. 1986;72(5):595-7. doi: 10.1007/BF00925480.
The growth of Plasmodium falciparum in vitro was quantitatively assessed by applying fluorometry using ethidium bromide. The fluorescence intensity of parasites stained with this dye was found to parallel the uptake of 3H-hypoxanthine into nucleic acids during one growth cycle of development. The assay system can be used as a substitute of morphological and radiometric methods in drug-sensitivity tests and for the screening of antimalarials.
通过应用溴化乙锭荧光测定法对恶性疟原虫的体外生长进行了定量评估。在用这种染料染色的寄生虫中，发现荧光强度与在一个生长发育周期中3H-次黄嘌呤掺入核酸的情况平行。该检测系统可替代形态学和放射性方法用于药物敏感性试验及抗疟药筛选。
