Int J Periodontics Restorative Dent. 2022 Mar-Apr;42(2):215-223. doi: 10.11607/prd.5563.
Allografts have been routinely used for immediate grafting of extraction sites as modalities of alveolar ridge preservation (ARP). Solvent-dehydrated bone allograft (SDBA), which is commonly utilized for socket grafting, exists in the form of cortical and cancellous particles. This study aims to provide a histologic comparison of cortical and cancellous SDBA for ARP. A total of 35 extraction sockets were allocated to receive either a cortical (17 sites) or cancellous (18 sites) SDBA, followed by application of a resorbable collagen wound dressing in both groups. At approximately 4 months, a bone core biopsy sample was obtained during implant placement. Histomorphometric assessment was then conducted to compare the differences between both forms of SDBA. Within its limitations, a higher percentage of vital bone was observed in the cortical bone group compared to the cancellous bone group (28.6% vs 20.1%, respectively, P = .042), while there was a lack of statistically significant differences among other fractions of the bone biopsy sample (residual graft particles and nonmineralized tissues such as connective tissue or other components).
同种异体移植物已被常规用于拔牙窝的即刻移植，作为牙槽嵴保存（ARP）的手段。溶剂脱水骨同种异体移植物（SDBA）常用于牙槽窝植骨，呈皮质和松质颗粒状。本研究旨在对 ARP 中皮质和松质 SDBA 进行组织学比较。共将 35 个拔牙窝分配给皮质 SDBA（17 个部位）或松质 SDBA（18 个部位），两组均应用可吸收胶原创面敷料。大约 4 个月后，在植入物放置期间获得骨芯活检样本。然后进行组织形态计量评估，以比较两种形式的 SDBA 之间的差异。在其局限性内，皮质骨组的活骨百分比高于松质骨组（分别为 28.6%和 20.1%，P =.042），而骨活检样本的其他部分（残留移植物颗粒和未矿化组织，如结缔组织或其他成分）之间没有统计学上的显著差异。
