Department of Maxillofacial and Plastic Surgery, Federal State Budgetary Educational Institution of Higher Education "Russian University of Medicine" of the Ministry of Healthcare of the Russian Federation, 127006 Moscow, Russia.
Department of Pathological Anatomy, North-Western State Medical University Named after I.I. Mechnikov, 191015 Saint Petersburg, Russia.
Medicina (Kaunas). 2024 Aug 8;60(8):1280. doi: 10.3390/medicina60081280.
An urgent issue is the preservation or reconstruction of the volume of bone tissue in planning and surgical treatment in the fields of medicine, such as traumatology, orthopedics, maxillofacial surgery and dentistry. After tooth extraction, resorption of the bone tissue of the alveolar crest of the jaws occurs, which must either be further eliminated by performing additional operations or using osteoplastic material for socket preservation at the extraction stage. The aim of the study was a comparative analysis of various osteoplastic materials used to preserve the volume of bone tissue in the preimplantation period. As part of the study, 80 patients were treated, who underwent socket preservation using xenografts, plasma enriched with growth factors, an autologous dentin matrix (ADM) and hydroxyapatite. The results of the treatment 16 weeks after removal were comprehensively analyzed using a morphometric analysis of the bone's volume, cone beam tomography and morphological examination of burr biopsy specimens, as well as by determining the stability of the installed implant at different stages of treatment. The lowest level of bone tissue resorption according to the CBCT data was noted in the ADM and xenograft groups. It should be noted that the use of osteoplastic material in jaw surgery when reconstructing alveolar defects is an essential procedure for preventing the atrophy of bone tissue.
一个紧迫的问题是在医学领域，如创伤学、骨科、颌面外科和牙科，在规划和手术治疗中保存或重建骨组织体积。拔牙后，颌骨牙槽嵴的骨组织吸收，必须通过进行额外的手术或在拔牙阶段使用骨形成材料来进一步消除。本研究的目的是对用于在植入前阶段保存骨组织体积的各种骨形成材料进行比较分析。作为研究的一部分，对 80 名患者进行了治疗，他们使用异种移植物、富含生长因子的血浆、自体牙本质基质（ADM）和羟基磷灰石进行了牙槽窝保存。在去除后 16 周，通过对骨体积的形态计量分析、锥形束 CT 和骨钻活检标本的形态学检查，以及在治疗的不同阶段确定安装的植入物的稳定性，对治疗结果进行了全面分析。根据 CBCT 数据，ADM 和异种移植物组的骨组织吸收水平最低。应当指出，在颌骨手术中使用骨形成材料来重建牙槽骨缺损是防止骨组织萎缩的必要程序。
