南非奥密克戎变异株高无症状携带率。
High Asymptomatic Carriage With the Omicron Variant in South Africa.
机构信息
Centre for the AIDS Programme of Research in South Africa, University of KwaZulu-Natal, Durban, South Africa.
Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
出版信息
Clin Infect Dis. 2022 Aug 24;75(1):e289-e292. doi: 10.1093/cid/ciac237.
We report a 23% asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) Omicron carriage rate in participants being enrolled into a clinical trial in South Africa, 15-fold higher than in trials before Omicron. We also found lower CD4 + T-cell counts in persons with human immunodeficiency virus (HIV) strongly correlated with increased odds of being SARS-CoV-2 polymerase chain reaction (PCR) positive.
我们报告了南非一项临床试验中无症状的严重急性呼吸综合征冠状病毒 2（SARS-CoV-2）奥密克戎携带率为 23%，是奥密克戎出现之前临床试验的 15 倍。我们还发现，艾滋病毒（HIV）感染者的 CD4+T 细胞计数较低与 SARS-CoV-2 聚合酶链反应（PCR）阳性的几率增加强烈相关。
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