Department of Ophthalmology, Wakaba Eye Hospital, Tokyo.
Strabismus. 2022 Jun;30(2):72-77. doi: 10.1080/09273972.2022.2055091. Epub 2022 Mar 31.
Age-related distance esotropia (ARDE) is thought to be caused by sagging eye syndrome. Sagging of the lateral rectus derives from the naturally occurring aging process and induces excyclotorsion of the eye. To date, no study has compared the cyclodeviation in ARDE with that in the age-matched individuals without strabismus. This study aimed to measure the objective cyclotorsion on fundus photographs of ARDE patients and compare the findings with those for normal age-matched individuals. Objective cyclotorsion was measured by determining the disc-to-fovea angle (DFA) on fundus photographs, which were obtained from two groups: 38 consecutive patients with ARDE (age, 74.1 ± 7.9 years), 76 normal age-matched controls (age, 73.9 ± 8.1 years). DFA in ARDE patients was not different from that in the control group (Welch's t-test: ARDE vs Control, right eye; 7.7° ± 2.9° vs 6.8° ± 3.9°, p = .18. Left eye; 10.0° ± 4.5° vs 9.4° ± 3.6°, p = .54. Sum of both eyes; 17.6° ± 5.8° vs 16.2° ± 4.7°, p = .21). These findings suggest sagging of the lateral rectus is not the sole cause of ARDE. Another aging-related factor, such as decreased phoria adaptation, might also be responsible for ARDE.
年龄相关性外斜视（ARDE）被认为是由眼下垂综合征引起的。外侧直肌的下垂源于自然发生的衰老过程，并引起眼的外旋。迄今为止，尚无研究比较 ARDE 患者的斜视度与无斜视的年龄匹配个体的斜视度。本研究旨在通过确定眼底照片上的视盘到黄斑角（DFA）来测量 ARDE 患者的客观眼旋转，并将结果与正常年龄匹配的个体进行比较。客观眼旋转通过确定眼底照片上的视盘到黄斑角（DFA）来测量，该照片来自两个组：38 名连续的 ARDE 患者（年龄，74.1±7.9 岁），76 名正常年龄匹配的对照组（年龄，73.9±8.1 岁）。ARDE 患者的 DFA 与对照组无差异（Welch 检验：ARDE 与对照组，右眼：7.7°±2.9°与 6.8°±3.9°，p=0.18.左眼：10.0°±4.5°与 9.4°±3.6°，p=0.54.双眼总和：17.6°±5.8°与 16.2°±4.7°，p=0.21）。这些发现表明外侧直肌的下垂不是 ARDE 的唯一原因。另一个与年龄相关的因素，如调节不足，也可能是 ARDE 的原因。
