Department of Chemistry and Biochemistry, Rowan University, 201 Mullica Hill Rd., Glassboro, NJ, USA.
Chem Commun (Camb). 2022 Apr 14;58(31):4909-4912. doi: 10.1039/d2cc00686c.
Herein we report the zirconooxaziridine promoted aziridination of alkenes using chloramine T as the quantitative source of N. The reaction works with high yields, diastereoselectivities and stereospecificity for a wide variety of substituted alkenes. A potential mechanism involving the formation of a zirconooxaziridine complex as the active catalyst has been proposed and initial mechanistic data would indicate that a highly associative mechanism is the predominant pathway for this transformation.
在此，我们报告了使用氯胺 T 作为定量氮源的锆噁唑啉促进的烯烃氮丙啶化反应。该反应具有高产率、高非对映选择性和对各种取代烯烃的立体选择性。提出了一种涉及形成锆噁唑啉配合物作为活性催化剂的可能机制，初步的机理数据表明，高度缔合的机制是该转化的主要途径。
