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唐氏综合征成人的即刻序贯双侧白内障手术。

Immediate sequential bilateral cataract surgery in adults with Down's syndrome.

机构信息

Hospital Universitario Puerta de Hierro, C/Joaquin Rodrigo, 1, 28222, Majadahonda, Madrid, Spain.

Hospital Universitario de la Princesa, C/Diego de Leon, 62, 28006, Madrid, Spain.

出版信息

Int Ophthalmol. 2022 Oct;42(10):2997-3004. doi: 10.1007/s10792-022-02285-7. Epub 2022 Mar 30.

Abstract

PURPOSE

To describe the cataract surgery outcomes in 34 adult patients with Down's syndrome in our center between 1996 and 2019.

SETTING

Clinical practice, tertiary hospital in Madrid, Spain.

DESIGN

Retrospective, descriptive study in which 34 patients with Down's syndrome who underwent cataract surgery in our center between 1996 and 2019 were included.

METHODS

Socio-demographic and clinical data such as the type of cataract, the keratometry and biometry, the type of surgery, the IOL material, and the complications before and after surgery were recovered.

RESULTS

Fifty-four eyes of 34 patients (23 female, 11 male, mean age 49 ± 8 years) underwent cataract surgery with general anesthesia. Immediately sequential, bilateral cataract surgery was performed in 18 patients (90% of bilateral cases). White cataract was found in 11 eyes (20.4%). Phacoemulsification technique was used in 51 eyes, extracapsular technique in 2 eyes (3.7%), and intracapsular technique in 1 eye (1.85%) (the only aphakic eye after surgery). The mean Km was 48.73 ± 4D, and the mean axial length was 25.2 ± 2.5 mm. The most frequent ocular comorbidity was myopia (27 eyes, 50%) followed by strabismus (11 eyes, 20.4%) and keratoconus (10 eyes, 18.5%). Posterior capsular rupture as a complication during surgery was found in 3 eyes (5.5%). The mean preoperative visual acuity was 0.8 ± 0.2 logMAR, and the mean postoperative visual acuity was 0.5 ± 0.18 logMAR.

CONCLUSIONS

Phacoemulsification technique can be performed in adults with Down's syndrome with an acceptable rate of complications. The lack of patient cooperation, the ocular comorbidities and the challenging biometric estimation must be considered in surgical planning. It seems reasonable to perform immediately sequential, bilateral cataract surgery when possible, in order to reduce the exposure to general anesthesia.

摘要

目的

描述我们中心 1996 年至 2019 年间 34 例唐氏综合征成人白内障手术的结果。

背景

临床实践,西班牙马德里的一家三级医院。

设计

回顾性描述性研究,纳入 1996 年至 2019 年间在我们中心接受白内障手术的 34 例唐氏综合征患者。

方法

收集患者的社会人口统计学和临床数据,包括白内障类型、角膜曲率和生物测量、手术类型、人工晶状体材料以及手术前后的并发症。

结果

34 例患者的 54 只眼(23 名女性,11 名男性,平均年龄 49±8 岁)接受了全身麻醉下的白内障手术。18 例患者(90%的双侧病例)进行了即刻序贯双侧白内障手术。11 只眼(20.4%)发现为白色白内障。51 只眼采用超声乳化技术,2 只眼(3.7%)采用囊外技术,1 只眼(1.85%)采用囊内技术(唯一术后无晶状体眼)。平均角膜曲率为 48.73±4D,平均眼轴长度为 25.2±2.5mm。最常见的眼部合并症是近视(27 只眼,50%),其次是斜视(11 只眼,20.4%)和圆锥角膜(10 只眼,18.5%)。术中发现 3 只眼(5.5%)后囊膜破裂。术前平均视力为 0.8±0.2 logMAR,术后平均视力为 0.5±0.18 logMAR。

结论

对于唐氏综合征成人,可以采用超声乳化技术进行白内障手术,并发症发生率可接受。在手术计划中,必须考虑到患者合作程度差、眼部合并症以及具有挑战性的生物测量评估。如果可能,应合理地进行即刻序贯双侧白内障手术,以减少全身麻醉的暴露。

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