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多形性胶质母细胞瘤的异时性骨转移:一种不寻常的表现。

Metachronous Osseous Metastases From Gliobliostoma Mutiforme: An Unusual Presentation.

作者信息

Krishnan Ajay S, Gupta Sweety, Mandal Shreyosi, Phulware Ravi H, Gupta Manoj

机构信息

Department of Radiation Oncology, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.

Department of Pathology, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.

出版信息

Cureus. 2022 Feb 25;14(2):e22587. doi: 10.7759/cureus.22587. eCollection 2022 Feb.

DOI:10.7759/cureus.22587
PMID:35355536
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8957711/
Abstract

Metastasis occurs very rarely in glioblastoma cases. Diagnosing metastatic glioblastoma has to follow a strict protocol to avoid misdiagnosis. Weiss's 1955 criteria, which is in prevalence, needs to be modified to include current standards of investigation. We report an interesting case of metachronous osseous metastasis from a primary glioblastoma with a complete response at a local site. We also suggest modifications to Weiss' criteria, which may improve its utility in establishing the diagnosis of metastatic glioblastoma.

摘要

胶质母细胞瘤病例中转移极为罕见。诊断转移性胶质母细胞瘤必须遵循严格的方案以避免误诊。普遍使用的1955年韦斯标准需要修订,纳入当前的检查标准。我们报告了一例原发性胶质母细胞瘤发生异时性骨转移且局部病灶完全缓解的有趣病例。我们还建议对韦斯标准进行修改,这可能会提高其在诊断转移性胶质母细胞瘤中的效用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a93e/8957711/fc536a638e9f/cureus-0014-00000022587-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a93e/8957711/53e7afc9c5a8/cureus-0014-00000022587-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a93e/8957711/304a7f1c1367/cureus-0014-00000022587-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a93e/8957711/fc536a638e9f/cureus-0014-00000022587-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a93e/8957711/53e7afc9c5a8/cureus-0014-00000022587-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a93e/8957711/304a7f1c1367/cureus-0014-00000022587-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a93e/8957711/fc536a638e9f/cureus-0014-00000022587-i03.jpg

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Regorafenib in Recurrent Glioblastoma Patients: A Large and Monocentric Real-Life Study.瑞戈非尼用于复发性胶质母细胞瘤患者:一项大型单中心真实世界研究。
Cancers (Basel). 2021 Sep 21;13(18):4731. doi: 10.3390/cancers13184731.
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Rev Assoc Med Bras (1992). 2019 Mar;65(3):424-433. doi: 10.1590/1806-9282.65.3.424. Epub 2019 Apr 11.
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Regorafenib compared with lomustine in patients with relapsed glioblastoma (REGOMA): a multicentre, open-label, randomised, controlled, phase 2 trial.
雷戈非尼对比洛莫司汀治疗复发性胶质母细胞瘤患者(REGOMA):一项多中心、开放标签、随机、对照、2 期临床试验。
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Extracranial metastasis of gliobastoma: Three illustrative cases and current review of the molecular pathology and management strategies.胶质母细胞瘤的颅外转移:三例说明性病例及分子病理学与管理策略的当前综述
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