Xie Zhiqin, Liu Jiawen, Yang Zhen, Tang Liping, Wang Shuilian, Du Yunyu, Yang Lina
Department of Nursing, First Affiliated Hospital of Nanchang University, Nanchang, China.
School of Nursing, Nanchang University, Nanchang, China.
Front Med (Lausanne). 2022 Mar 9;9:839070. doi: 10.3389/fmed.2022.839070. eCollection 2022.
The occurrence of postoperative reintubation (POR) in patients after general anesthesia (GA) is often synonymous with a poor prognosis in patients. This is the first review analyzing scientific literature to identify risk factors of POR after general anesthesia. The purpose of this study was to collect currently published studies to determine the most common and consistent risk factors associated with POR after GA.
We have retrieved all relevant research published before April 2021 from PubMed, Embase, Web of Science, and the Cochrane Library electronic databases. These studies were selected according to the inclusion and exclusion criteria. The Z test determined the combined odds ratio (OR) of risk factors. We used OR and its corresponding 95% confidence interval (CI) to identify significant differences in risk factors. The quality of the study was evaluated with the NOS scale, and meta-analysis was carried out with Cochrane Collaboration's Revman 5.0 software.
A total of 10 studies were included, with a total of 7,789 recipients of POR. We identified 7 risk factors related to POR after GA: ASA ≥ 3 (OR = 3.58), COPD (OR = 2.09), thoracic surgery (OR = 17.09), airway surgery (OR = 9.93), head-and-neck surgery (OR = 3.49), sepsis (OR = 3.50), DVT (OR = 4.94).
Our meta-analysis showed that ASA ≥ 3, COPD, thoracic surgery, airway surgery, head-and-neck surgery, sepsis and DVT were associated with POR after GA.
https://www.crd.york.ac.uk/prospero/display_record.php?, Identifier: CRD42021252466.
全身麻醉（GA）后患者发生术后再次插管（POR）通常意味着患者预后不良。这是第一篇分析科学文献以确定全身麻醉后POR危险因素的综述。本研究的目的是收集当前已发表的研究，以确定与全身麻醉后POR相关的最常见和一致的危险因素。
我们从PubMed、Embase、Web of Science和Cochrane图书馆电子数据库中检索了2021年4月之前发表的所有相关研究。这些研究根据纳入和排除标准进行选择。Z检验确定危险因素的合并比值比（OR）。我们使用OR及其相应的95%置信区间（CI）来确定危险因素的显著差异。采用NOS量表评估研究质量，并使用Cochrane协作网的Revman 5.0软件进行荟萃分析。
共纳入10项研究，共有7789例POR患者。我们确定了7个与全身麻醉后POR相关的危险因素：美国麻醉医师协会（ASA）分级≥3（OR = 3.58）、慢性阻塞性肺疾病（COPD，OR = 2.09）、胸外科手术（OR = 17.09）、气道手术（OR = 9.93）、头颈外科手术（OR = 3.49）、脓毒症（OR = 3.50）、深静脉血栓形成（DVT，OR = 4.94）。
我们的荟萃分析表明，ASA分级≥3、COPD、胸外科手术、气道手术、头颈外科手术、脓毒症和DVT与全身麻醉后POR相关。
https://www.crd.york.ac.uk/prospero/display_record.php?，标识符：CRD42021252466。
