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[人肾素分泌细胞。形态学研究]

[The human renin-secreting cell. A morphological study].

作者信息

Lindop G B, Gardiner D S

出版信息

Ann Endocrinol (Paris). 1986;47(3):133-44.

PMID:3535634
Abstract

The availability of specific antisera to renin and the techniques of immunocytochemistry have facilitated the microscope study of renin-secreting cells. These techniques have been used in recent studies in the developing kidney as well as in both normal and pathological adult kidney. This work has clarified the close relationship between myoepithelioid cell and the blood vessel. The use of ultrastructural immunocytochemistry has led to new insights into the intracellular processing, storage and secretion of renin. These recent morphological studies are reviewed with the emphasis on the human renin-secreting cell within the kidney.

摘要

肾素特异性抗血清的可得性以及免疫细胞化学技术促进了对肾素分泌细胞的显微镜研究。这些技术已被用于近期关于发育中肾脏以及正常和病理状态下成年肾脏的研究。这项工作阐明了肌上皮样细胞与血管之间的密切关系。超微结构免疫细胞化学的应用为肾素的细胞内加工、储存和分泌带来了新的见解。本文对这些近期的形态学研究进行综述,重点关注肾脏内的人肾素分泌细胞。

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